Multi-functional norrin is a ligand for the LGR4 receptor.
about
The DAN family: modulators of TGF-β signaling and beyondA rapid and affordable screening platform for membrane protein trafficking.Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for SignalingCanonical WNT signaling components in vascular development and barrier formation.Wnt signaling pathway in retinal vascularizationLocal control of intestinal stem cell homeostasis by enteroendocrine cells in the adult Drosophila midgutNorrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function.A naturally occurring Lgr4 splice variant encodes a soluble antagonist useful for demonstrating the gonadal roles of Lgr4 in mammals.Updating the Wnt pathways.The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment.Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.The Intracellular Loop 2 F328S Frizzled-4 Mutation Implicated in Familial Exudative Vitreoretinopathy Impairs Dishevelled Recruitment.Mutation spectrum of the Norrie disease pseudoglioma (NDP) gene in Indian patients with FEVRLgr4 in ocular development and glaucomaThe R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strengthRSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling.LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.Agonists and Antagonists of TGF-β Family Ligands.Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.Glycoprotein hormones and their receptors emerged at the origin of metazoansWnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells.WNT signaling, the development of the sympathoadrenal-paraganglionic system and neuroblastoma.Norrin treatment improves ganglion cell survival in an oxygen-induced retinopathy model of retinal ischemia.A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits.LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.Introgression of regulatory alleles and a missense coding mutation drive plumage pattern diversity in the rock pigeonThe evolution and expression of panarthropod frizzled genes
P2860
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P2860
Multi-functional norrin is a ligand for the LGR4 receptor.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Multi-functional norrin is a ligand for the LGR4 receptor.
@en
type
label
Multi-functional norrin is a ligand for the LGR4 receptor.
@en
prefLabel
Multi-functional norrin is a ligand for the LGR4 receptor.
@en
P2093
P2860
P356
P1476
Multi-functional norrin is a ligand for the LGR4 receptor
@en
P2093
Aaron J W Hsueh
Cheng Deng
Chih-Lun Hsiao
Ching-Wei Luo
Yuan Cheng
P2860
P304
P356
10.1242/JCS.123471
P407
P577
2013-02-26T00:00:00Z