Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.
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Astrocytes As the Main Players in Primary Degenerative Disorders of the Human Central Nervous SystemRole of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesityKynurenines in the mammalian brain: when physiology meets pathologyThe neural and genetic basis of executive function: attention, cognitive flexibility, and response inhibition.nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult ratsInflammation and the two-hit hypothesis of schizophrenia.Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia.Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.Systemic L-Kynurenine sulfate administration disrupts object recognition memory, alters open field behavior and decreases c-Fos immunopositivity in C57Bl/6 mice.Neurological and psychiatric disorders as a neuroglial failure.Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of ratsIndoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge.N-acetylserotonin and aging-associated cognitive impairment and depression.Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia.Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamineA genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders.The effect of transient increases in kynurenic acid and quinolinic acid levels early in life on behavior in adulthood: Implications for schizophrenia.Sustained elevation of kynurenic Acid in the cerebrospinal fluid of patients with herpes simplex virus type 1 encephalitis.Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges.Targeting of NMDA receptors in new treatments for schizophrenia.Novel investigational drugs targeting IL-6 signaling for the treatment of depression.Potential Use of Nicotinic Receptor Agonists for the Treatment of Chemotherapy-Induced Cognitive Deficits.Preferential Disruption of Prefrontal GABAergic Function by Nanomolar Concentrations of the α7nACh Negative Modulator Kynurenic Acid.Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior.Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malariaKynurenines and Glutamate: Multiple Links and Therapeutic Implications.Role of Adiposity-Driven Inflammation in Depressive Morbidity.Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis.Chronic Antipsychotic Treatment in the Rat - Effects on Brain Interleukin-8 and Kynurenic Acid.Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo.Exposure to Kynurenic Acid during Adolescence Increases Sign-Tracking and Impairs Long-Term Potentiation in Adulthood.Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome.Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders.Biochemical and Clinical Impact of Organic Uremic Retention Solutes: A Comprehensive Update.Quantitative Analysis of Kynurenine Aminotransferase II in the Adult Rat Brain Reveals High Expression in Proliferative Zones and Corpus Callosum.Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats.
P2860
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P2860
Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Acute elevations of brain kynu ...... ositive modulator galantamine.
@en
type
label
Acute elevations of brain kynu ...... ositive modulator galantamine.
@en
prefLabel
Acute elevations of brain kynu ...... ositive modulator galantamine.
@en
P2093
P2860
P1433
P1476
Acute elevations of brain kynu ...... ositive modulator galantamine.
@en
P2093
Hui-Qiu Wu
John P Bruno
Kathleen S Alexander
Robert Schwarcz
P2860
P2888
P304
P356
10.1007/S00213-011-2539-2
P577
2011-10-26T00:00:00Z