β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. - Wikidata - wikimedia - TriplyDB

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

http://www.wikidata.org/entity/Q36887393

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The regulation of MMP targeting to invadopodia during cancer metastasis β1 and β4 integrins: from breast development to clinical practice The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation.A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.Invadosomes in their natural habitat.5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.p53 in cell invasion, podosomes, and invadopodia Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Stimulators of mineralization limit the invasive phenotype of human osteosarcoma cells by a mechanism involving impaired invadopodia formation.Regulation of invadopodia by the tumor microenvironment.Response to imatinib as a function of target kinase expression in recurrent glioblastoma.Podosomes and invadopodia: tools to breach vascular basement membrane.Helical buckling of actin inside filopodia generates traction.Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.Profilin1 regulates invadopodium maturation in human breast cancer cells ABL tyrosine kinase inhibition variable effects on the invasive properties of different triple negative breast cancer cell lines.Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma Protein tyrosine phosphatase SHP2 promotes invadopodia formation through suppression of Rho signaling Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells.Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2.Regulation of invadopodia by mechanical signaling.Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade.Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation.Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.Invading one step at a time: the role of invadopodia in tumor metastasis.Cellular traction stresses mediate extracellular matrix degradation by invadopodia Spatial regulation of tumor cell protrusions by RhoC.Coupling between acto-adhesive machinery and ECM degradation in invadosomes.Natural history of hepatic metastases from colorectal cancer--pathobiological pathways with clinical significance.Digging a little deeper: the stages of invadopodium formation and maturation.Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.Molecular mechanisms of tumour invasion: regulation by calcium signals.

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P2860

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

http://www.wikidata.org/entity/Q36887393

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

@en

type

label

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

@en

prefLabel

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.

@en

P1433

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MBC.E12-12-0908

P1433

Molecular Biology of the Cell

P1476

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation

@en

P2093

Anthony J Koleske

http://www.w3.org/2001/XMLSchema#string

Brian T Beaty

http://www.w3.org/2001/XMLSchema#string

John Condeelis

http://www.w3.org/2001/XMLSchema#string

Jose J Bravo-Cordero

http://www.w3.org/2001/XMLSchema#string

Mark A Simpson

http://www.w3.org/2001/XMLSchema#string

Robert J Eddy

http://www.w3.org/2001/XMLSchema#string

P2860

A novel protease-docking function of integrin at invadopodia

Crystal structure of the extracellular segment of integrin alpha Vbeta3

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

Anti-integrin monoclonal antibodies

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Degrading devices: invadosomes in proteolytic cell invasion

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actin

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1661-75, S1-11

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scholarly article

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10.1091/MBC.E12-12-0908

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11

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24

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2013-04-03T00:00:00Z

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23552693

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3667720

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