A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
about
DNA methylation age of human tissues and cell typesDNA modifications: function and applications in normal and disease StatesDNA methylation and healthy human agingThe Future is The Past: Methylation QTLs in SchizophreniaEffects of negative stressors on DNA methylation in the brain: implications for mood and anxiety disordersH3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cellsFunctional normalization of 450k methylation array data improves replication in large cancer studies.Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective.Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach.B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data.Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder.Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region.Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfiDNA methylation as a putative mechanism for reduced dendritic spine density in the superior temporal gyrus of subjects with schizophrenia.Alterations in DNA methylation of Fkbp5 as a determinant of blood-brain correlation of glucocorticoid exposure.Accounting for cellular heterogeneity is critical in epigenome-wide association studies.Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age.Common DNA methylation alterations in multiple brain regions in autism.DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways.Epigenetic alterations in depression and antidepressant treatmentAlzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's diseaseThe molecular bases of the suicidal brain.Epigenomics of Alzheimer's disease.Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophreniaDevelopmental regulation of human cortex transcription and its clinical relevance at single base resolution.Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites.The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder.Temporal lobe epilepsy: a unique window into living human brain epigenetic gene regulation.Nonparametric Bayesian clustering to detect bipolar methylated genomic loci.Concordant and discordant DNA methylation signatures of aging in human blood and brain.Sex differences of leukocytes DNA methylation adjusted for estimated cellular proportions.Substantial DNA methylation differences between two major neuronal subtypes in human brain.Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor AgeAssociation of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.High Precision DNA Modification Analysis of HCG9 in Major Psychosis.CpG methylation differences between neurons and glia are highly conserved from mouse to human.Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease.
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P2860
A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A cell epigenotype specific mo ...... in region and major depression
@en
type
label
A cell epigenotype specific mo ...... in region and major depression
@en
prefLabel
A cell epigenotype specific mo ...... in region and major depression
@en
P2860
P356
P1433
P1476
A cell epigenotype specific mo ...... in region and major depression
@en
P2093
Martin J Aryee
Zachary A Kaminsky
P2860
P304
P356
10.4161/EPI.23924
P50
P577
2013-02-20T00:00:00Z