TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.
about
FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locusImmune regulation by histone deacetylases: a focus on the alteration of FOXP3 activityUbiquitin-dependent regulation of Foxp3 and Treg functionTreg functional stability and its responsiveness to the microenvironmentStructural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell FunctionFOXP3+ regulatory T cells and their functional regulationHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyFoxp3 protein stability is regulated by cyclin-dependent kinase 2Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritisEos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cellsUbiquitous points of control over regulatory T cells.Rapid temporal control of Foxp3 protein degradation by sirtuin-1.All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus.Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function.Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cellsEndurance exercise diverts the balance between Th17 cells and regulatory T cellsHistone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells.IL-6 promotes cardiac graft rejection mediated by CD4+ cells.Histone/protein deacetylases and T-cell immune responsesPim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal PhosphorylationAn N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes.MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 ExpressionPrevention of allograft rejection by amplification of Foxp3(+)CD4(+)CD25(+) regulatory T cellsMammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T-cell population under TH17-polarizing conditionsRegulatory T cells modulate staphylococcal enterotoxin B-induced effector T-cell activation and acceleration of colitis.Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications.CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injuryUsing histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance.The T(reg)/Th17 cell balance: a new paradigm for autoimmunity.Epigenetic mechanisms of regulation of Foxp3 expression.Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells.Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers.Protective effect of cytosolic phospholipase A2 inhibition against inflammation and degeneration by promoting regulatory T cells in rats with experimental autoimmune encephalomyelitis.Treating arthritis by immunomodulation: is there a role for regulatory T cells?Harnessing regulatory T cells for the therapy of lupus and other autoimmune diseases.Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function.Physiologic control of the functional status of Foxp3+ regulatory T cells.The dual role of the X-linked FoxP3 gene in human cancers
P2860
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P2860
TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
TGF-beta and IL-6 signals modu ...... occupancy by acetylated FOXP3.
@en
type
label
TGF-beta and IL-6 signals modu ...... occupancy by acetylated FOXP3.
@en
prefLabel
TGF-beta and IL-6 signals modu ...... occupancy by acetylated FOXP3.
@en
P2093
P2860
P356
P1476
TGF-beta and IL-6 signals modu ...... occupancy by acetylated FOXP3
@en
P2093
Arabinda Samanta
Geng Zhang
Kathryn Bembas
Makoto Katsumata
Mark I Greene
Sandra J Saouaf
Wayne W Hancock
Xiaomin Song
P2860
P304
14023-14027
P356
10.1073/PNAS.0806726105
P407
P50
P577
2008-09-08T00:00:00Z