Yeast Dam1p is required to maintain spindle integrity during mitosis and interacts with the Mps1p kinase.
about
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplicationImplication of a novel multiprotein Dam1p complex in outer kinetochore functionVisualizing kinetochore architectureLoss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpointMps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassemblyKinetochore protein interactions and their regulation by the Aurora kinase Ipl1pThe yeast DASH complex forms closed rings on microtubules.Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregationYeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domainThe yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p.Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association.Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrityYeast Dam1p has a role at the kinetochore in assembly of the mitotic spindleThe spindle checkpoint, aneuploidy, and cancer.Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions.Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.An alpha-tubulin mutant demonstrates distinguishable functions among the spindle assembly checkpoint genes in Saccharomyces cerevisiae.Mps1p regulates meiotic spindle pole body duplication in addition to having novel roles during sporulation.Centrosomes and checkpoints: the MPS1 family of kinases.Laulimalide and peloruside A inhibit mitosis of Saccharomyces cerevisiae by preventing microtubule depolymerisation-dependent steps in chromosome separation and nuclear positioning.The mitotic spindle is required for loading of the DASH complex onto the kinetochore.Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation.The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distressSpindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest.Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complexMeiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregationMps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.The composition, functions, and regulation of the budding yeast kinetochoreStructure-function insights into the yeast Dam1 kinetochore complex.Ringing the changes: emerging roles for DASH at the kinetochore-microtubule Interface.Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation.The phosphorylation of a kinetochore protein Dam1 by Aurora B/Ipl1 kinase promotes chromosome bipolar attachment in yeast.Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms.Mps1 promotes chromosome meiotic chromosome bi-orientation through Dam1.TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress.
P2860
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P2860
Yeast Dam1p is required to maintain spindle integrity during mitosis and interacts with the Mps1p kinase.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Yeast Dam1p is required to mai ...... teracts with the Mps1p kinase.
@en
type
label
Yeast Dam1p is required to mai ...... teracts with the Mps1p kinase.
@en
prefLabel
Yeast Dam1p is required to mai ...... teracts with the Mps1p kinase.
@en
P2093
P2860
P356
P1476
Yeast Dam1p is required to mai ...... teracts with the Mps1p kinase.
@en
P2093
A R Castillo
J B Bachant
T H Giddings
P2860
P304
P356
10.1091/MBC.10.7.2377
P577
1999-07-01T00:00:00Z