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Persistent HIV-1 replication maintains the tissue reservoir during therapy

Persistent HIV-1 replication maintains the tissue reservoir during therapy

http://www.wikidata.org/entity/Q36897321

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Targeting the latent reservoir to achieve functional HIV cure Barriers to a cure for HIV in women Targeting the Brain Reservoirs: Toward an HIV Cure Perspectives for immunotherapy: which applications might achieve an HIV functional cure?Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV Efficient Inhibition of HIV Replication in the Gastrointestinal and Female Reproductive Tracts of Humanized BLT Mice by EFdA Cardiovascular Disease, Statins, and HIV Latency reversal and viral clearance to cure HIV-1.A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients.Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus Long-acting slow effective release antiretroviral therapy.HIV-Tat regulates macrophage gene expression in the context of neuroAIDS.Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques.What Integration Sites Tell Us about HIV Persistence LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV Tissue reservoirs of HIV Defining HIV and SIV Reservoirs in Lymphoid Tissues.Strategies to target non-T-cell HIV reservoirs Lack of concordance between residual viremia and viral variants driving de novo infection of CD4(+) T cells on ART.Defective proviruses rapidly accumulate during acute HIV-1 infection Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.Prolonged persistence of a novel replication-defective HIV-1 variant in plasma of a patient on suppressive therapy HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer.HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART.HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy.Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs.Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection Factors Associated with the Size of HIV DNA Reservoir.International AIDS Society global scientific strategy: towards an HIV cure 2016.A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages.Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma.HIV-1 latent reservoir: size matters Eradication of HIV from Tissue Reservoirs: Challenges for the Cure.HIV persistence: clonal expansion of cells in the latent reservoir.Dual antiretroviral therapy for HIV infection.

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Persistent HIV-1 replication maintains the tissue reservoir during therapy

http://www.wikidata.org/entity/Q36897321

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

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2016年论文

@zh

2016年论文

@zh-cn

name

Persistent HIV-1 replication maintains the tissue reservoir during therapy

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type

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Persistent HIV-1 replication maintains the tissue reservoir during therapy

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Persistent HIV-1 replication maintains the tissue reservoir during therapy

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Persistent HIV-1 replication maintains the tissue reservoir during therapy

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Angela R McLean

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Ashley T Haase

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Courtney V Fletcher

http://www.w3.org/2001/XMLSchema#string

Eun-Young Kim

http://www.w3.org/2001/XMLSchema#string

Helen R Fryer

http://www.w3.org/2001/XMLSchema#string

John Archer

http://www.w3.org/2001/XMLSchema#string

Ramon Lorenzo-Redondo

http://www.w3.org/2001/XMLSchema#string

Sudhir Penugonda

http://www.w3.org/2001/XMLSchema#string

Timothy W Schacker

http://www.w3.org/2001/XMLSchema#string

Trevor Bedford

http://www.w3.org/2001/XMLSchema#string

P2860

The population genetics of dN/dS

A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children

Why time matters: codon evolution and the temporal dynamics of dN/dS

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

Bayesian phylogeography finds its roots

Not so different after all: a comparison of methods for detecting amino acid sites under selection

BEAST 2: a software platform for Bayesian evolutionary analysis

HyPhy: hypothesis testing using phylogenies

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51-56

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scholarly article

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10.1038/NATURE16933

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P433

7588

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530

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Michael Henry Malim

Jeffrey G Chipman

Steven M. Wolinsky

Yoon-Seok Chung

Sergei L Kosakovsky Pond

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2016-01-27T00:00:00Z

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26814962

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4865637

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