Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.
about
Recent advances in understanding the extracellular calcium-sensing receptorAutosomal Dominant Hypocalcemia (Hypoparathyroidism) Types 1 and 2Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasisKnockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors.Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy.Diseases associated with calcium-sensing receptorMutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy.Calcimimetic and calcilytic therapies for inherited disorders of the calcium-sensing receptor signalling pathway.Cinacalcet corrects hypercalcemia in mice with an inactivating Gα11 mutation.Cinacalcet Rectifies Hypercalcemia in a Patient With Familial Hypocalciuric Hypercalcemia Type 2 (FHH2) Caused by a Germline Loss-of-Function Gα11 Mutation.
P2860
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P2860
Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Allosteric Modulation of the C ...... ic and Hypocalcemic Disorders.
@en
type
label
Allosteric Modulation of the C ...... ic and Hypocalcemic Disorders.
@en
prefLabel
Allosteric Modulation of the C ...... ic and Hypocalcemic Disorders.
@en
P2093
P2860
P50
P356
P1476
Allosteric Modulation of the C ...... ic and Hypocalcemic Disorders.
@en
P2093
Allen M Spiegel
Jianxin Hu
M Andrew Nesbit
Nigel Rust
Valerie N Babinsky
P2860
P304
10876-10885
P356
10.1074/JBC.M115.696401
P407
P577
2016-03-18T00:00:00Z