The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.
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Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptideStructural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide.Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegenerationX-ray and solution structures of Cu(II) GHK and Cu(II) DAHK complexes: influence on their redox properties.Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptideNanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide.Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's diseaseOxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.Aggregation of amyloids in a cellular context: modelling and experiment.Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer's Drug Discovery.A first-principle calculation of the XANES spectrum of Cu(2+) in water.Substoichiometric levels of Cu2+ ions accelerate the kinetics of fiber formation and promote cell toxicity of amyloid-{beta} from Alzheimer disease.Structural studies of copper(I) complexes of amyloid-beta peptide fragments: formation of two-coordinate bis(histidine) complexes.The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants.Mo polyoxometalate nanoclusters capable of inhibiting the aggregation of Aβ-peptide associated with Alzheimer's disease.Development and Application of a Nonbonded Cu(2+) Model That Includes the Jahn-Teller EffectProbing oligomerization of amyloid beta peptide in silico.Role of Copper in the Onset of Alzheimer's Disease Compared to Other Metals.Benchmarking of copper(II) LFMM parameters for studying amyloid-β peptides.
P2860
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P2860
The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The structure of the amyloid-b ...... ing site in Alzheimer disease.
@en
type
label
The structure of the amyloid-b ...... ing site in Alzheimer disease.
@en
prefLabel
The structure of the amyloid-b ...... ing site in Alzheimer disease.
@en
P2093
P2860
P1433
P1476
The structure of the amyloid-b ...... ing site in Alzheimer disease.
@en
P2093
Joseph N Varghese
Kevin J Barnham
Stephen J Titmuss
V Chandana Epa
Victor A Streltsov
P2860
P304
P356
10.1529/BIOPHYSJ.108.134429
P407
P577
2008-07-03T00:00:00Z