Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
about
ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomesThe Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiaeYeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosisBudding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis.Differential association of the conserved SUMO ligase Zip3 with meiotic double-strand break sites reveals regional variations in the outcome of meiotic recombination.The meiotic checkpoint network: step-by-step through meiotic prophaseRegulation of fragile sites expression in budding yeast by MEC1, RRM3 and hydroxyurea.Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis.DNA double-strand break repair in Caenorhabditis elegansBudding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatidsEssential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugsExploring Biomolecular Literature with EVEX: Connecting Genes through Events, Homology, and Indirect Associations.Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis.Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycleATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencingThree distinct modes of Mec1/ATR and Tel1/ATM activation illustrate differential checkpoint targeting during budding yeast early meiosis.Recombinogenic conditions influence partner choice in spontaneous mitotic recombination.Pch2 prevents Mec1/Tel1-mediated Hop1 phosphorylation occurring independently of Red1 in budding yeast meiosis.DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line.
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P2860
Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
description
2007 nî lūn-bûn
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2007年の論文
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name
Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
@en
type
label
Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
@en
prefLabel
Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
@en
P1433
P1476
Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM
@en
P2093
Jesús A Carballo
Rita S Cha
P2860
P2888
P304
P356
10.1007/S10577-007-1145-Y
P577
2007-01-01T00:00:00Z