A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
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Function Over Form: Modeling Groups of Inherited Neurological Conditions in ZebrafishMicroenvironment-derived factors driving metastatic plasticity in melanoma.Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes.Zebrafish models for functional and toxicological screening of nanoscale drug delivery systems: promoting preclinical applications.Melanoma genome evolution across species.TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.Intratumoral Heterogeneity of the Epigenome.The Vital Relationship Between Nutrition and Health in Zebrafish.The Conundrum of Genetic "Drivers" in Benign Conditions.Leveraging premalignant biology for immune-based cancer prevention.Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafishReengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity.Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis.An ongoing role for Wnt signaling in differentiating melanocytes in vivoThe Power of Zebrafish in Personalised Medicine.Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer.Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells.Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes.Preclinical Advances with Multiphoton Microscopy in Live Imaging of Skin Cancers.Live imaging of stem cells: answering old questions and raising new ones.Targeting the cancer epigenome for therapy.Imaging to study solid tumour origin and progression: lessons from research and clinical oncology.From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma.Insights from zebrafish on human pigment cell disease and treatment.Super-Enhancer-Driven Transcriptional Dependencies in Cancer.A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.Optical Control of Tumor Induction in the ZebrafishSingle-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types.Melanoma topology reveals a stem-like phenotype that promotes angiogenesis.A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates.SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.Clinical and molecular insights into adenoid cystic carcinoma: Neural crest‐like stemness as a target.Modeling Myeloid Malignancies Using Zebrafish.Quo natas, Danio?—Recent Progress in Modeling Cancer in Zebrafish.Tumorigenesis as a process of gradual loss of original cell identity and gain of properties of neural precursor/progenitor cells.Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells.
P2860
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P2860
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A zebrafish melanoma model rev ...... ity during melanoma initiation
@en
type
label
A zebrafish melanoma model rev ...... ity during melanoma initiation
@en
prefLabel
A zebrafish melanoma model rev ...... ity during melanoma initiation
@en
P2093
P2860
P50
P356
P1433
P1476
A zebrafish melanoma model rev ...... ity during melanoma initiation
@en
P2093
Andrew J Thomas
Ann-Christin Puller
Christie Ciarlo
Cristina Santoriello
Dominick A Matos
Ellen van Rooijen
Elliott J Hagedorn
Leonard I Zon
Rachel D Fogley
Richard M White
P2860
P304
P356
10.1126/SCIENCE.AAD2197
P407
P577
2016-01-28T00:00:00Z