about
PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondriaRITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.Glycosylated Notch and CancerMolecular classification of gastric cancer: Towards a pathway-driven targeted therapyNon-canonical Notch signaling: emerging role and mechanismEpigenetic silencing of Notch signaling in gastrointestinal cancersNotch ligand endocytosis: mechanistic basis of signaling activityThe Regulatory Role of MicroRNAs in EMT and CancerTargeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cellsNotch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomasNotch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eyeTranscriptome profiling of whole blood cells identifies PLEK2 and C1QB in human melanomaNotch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation.NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.sel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegansMatrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancerRac1 as a potential therapeutic target for chemo-radioresistant head and neck squamous cell carcinomas (HNSCC)Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44+ Gastric Cancer Stem Cells.Notch signaling activation suppresses v-Src-induced transformation of neural cells by restoring TGF-β-mediated differentiationHistone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.Differential expression of the Notch1 receptor, and its ligands Dll1, Dll3 and Dll4 in distinct human pituitary adenoma subtypes.Brain angiogenesis in developmental and pathological processes: mechanism and therapeutic intervention in brain tumors.Single nucleotide polymorphism rs3124599 in Notch1 is associated with the risk of lung cancer in northeast Chinese non-smoking females.Notch1 signaling is activated in cells expressing embryonic stem cell proteins in human primary nasopharyngeal carcinoma.Cell signalling pathway regulation by RanBPM: molecular insights and disease implications.Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.The functional role of Notch signaling in human gliomas.Notch activation as a driver of osteogenic sarcoma.Targeting Notch signaling pathway to overcome drug resistance for cancer therapyRole of liver stem cells in hepatocarcinogenesis.Dissecting and circumventing the requirement for RAM in CSL-dependent Notch signaling.Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen.Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinomaDCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.More complicated than it looks: assembly of Notch pathway transcription complexes.Loss of the Notch effector RBPJ promotes tumorigenesis.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Notch and cancer: a double-edged sword.
@en
type
label
Notch and cancer: a double-edged sword.
@en
prefLabel
Notch and cancer: a double-edged sword.
@en
P1476
Notch and cancer: a double-edged sword.
@en
P2888
P304
P356
10.1007/S00018-007-7164-1
P577
2007-11-01T00:00:00Z