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Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityLineage relationship of effector and memory T cellsTsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programsInsight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and functionLineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscapeThe interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiationThe transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infectionFoxO3 is a negative regulator of primary CD8+ T-cell expansion but not of memory formationICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.Molecular regulation of effector and memory T cell differentiationmTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.Transforming growth factor-β signaling is constantly shaping memory T-cell population.The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection.Oct1 and OCA-B are selectively required for CD4 memory T cell functionAsymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection.Costimulatory and Coinhibitory Receptor Pathways in Infectious DiseaseInhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.Transcription Factor Bcl11b Controls Effector and Memory CD8 T cell Fate Decision and Function during Poxvirus InfectionDifferential roles of KLF4 in the development and differentiation of CD8+ T cells.Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory.Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection.Heterogeneity in the differentiation and function of CD8⁺ T cells.Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes.Extending the lifespan and efficacies of immune cells used in adoptive transfer for cancer immunotherapies-A review.Enhanced cytotoxic T-cell function and inhibition of tumor progression by Mst1 deficiency.Metabolic programming in chronically stimulated T cells: Lessons from cancer and viral infections.A role for the histone H2A deubiquitinase MYSM1 in maintenance of CD8+ T cells.Understanding memory CD8+ T cells.Constitutive Glycolytic Metabolism Supports CD8(+) T Cell Effector Memory Differentiation during Viral Infection.miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb.Metabolism in Immune Cell Differentiation and Function.CD8+ T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections.Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5.IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance.Gammaherpesvirus latency differentially impacts the generation of primary versus secondary memory CD8+ T cells during subsequent infection.Antigen-specific culture of memory-like CD8 T cells for adoptive immunotherapy.FAM13A is associated with non-small cell lung cancer (NSCLC) progression and controls tumor cell proliferation and survival.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Differentiation of CD8 memory T cells depends on Foxo1.
@en
type
label
Differentiation of CD8 memory T cells depends on Foxo1.
@en
prefLabel
Differentiation of CD8 memory T cells depends on Foxo1.
@en
P2093
P2860
P356
P1476
Differentiation of CD8 memory T cells depends on Foxo1.
@en
P2093
Ananda W Goldrath
Andrew L Doedens
Rodrigo Hess Michelini
Stephen M Hedrick
P2860
P304
P356
10.1084/JEM.20130392
P407
P577
2013-05-27T00:00:00Z