Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L

Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L

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http://www.wikidata.org/entity/Q36910012
Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap.Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism.Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies.Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.Instability in the central region of tropomyosin modulates the function of its overlapping ends.Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.The Relaxation Properties of Myofibrils Are Compromised by Amino Acids that Stabilize α-Tropomyosin.Overview of the Muscle Cytoskeleton.Pathogenesis associated with a restrictive cardiomyopathy mutant in cardiac troponin T is due to reduced protein stability and greatly increased myofilament Ca2+ sensitivity.Functional role of the core gap in the middle part of tropomyosin.The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.Investigating the effects of tropomyosin mutations on its flexibility and interactions with filamentous actin using molecular dynamics simulation.Calcium in Brugada Syndrome: Questions for Future Research
P2860

Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L

Item
http://www.wikidata.org/entity/Q36910012
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
@zh-cn
name
Conserved Asp-137 is important ...... se model expressing α-TM-D137L
@en
type
label
Conserved Asp-137 is important ...... se model expressing α-TM-D137L
@en
prefLabel
Conserved Asp-137 is important ...... se model expressing α-TM-D137L
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Conserved Asp-137 is important ...... se model expressing α-TM-D137L
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932