Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src.
about
Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase diseaseKSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseDrosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythmsAltered metabolism and persistent starvation behaviors caused by reduced AMPK function in DrosophilaPhosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24)HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA.Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutantsIdentification of CDK4 sequences involved in cyclin D1 and p16 bindingLck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activityLck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid raftsRole of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptorWaaP of Pseudomonas aeruginosa is a novel eukaryotic type protein-tyrosine kinase as well as a sugar kinase essential for the biosynthesis of core lipopolysaccharidePSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complexDecoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein KinasesIdentification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signalingSrc kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.Mutations in v-Src SH3 and catalytic domains that jointly confer temperature-sensitive transformation with minimal temperature-dependent changes in cellular tyrosine phosphorylationBacterial expression of an active tyrosine kinase from a protein A/truncated c-src fusion protein.Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway.Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stabilityA vesicle surface tyrosine kinase regulates phagosome maturationA FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly.A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.Characterization of a Hank's type serine/threonine kinase and serine/threonine phosphoprotein phosphatase in Pseudomonas aeruginosaThe Crithidia fasciculata CRK gene encodes a novel cdc2-related protein containing large inserts between highly conserved domainsPotential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.Functional domains of fused, a serine-threonine kinase required for signaling in DrosophilaA minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the high-affinity IgE receptor.A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog.Interacting protein kinases involved in the regulation of flagellar length.Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src.Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice.A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein deliveryReplacement of lys 622 in the ATP binding domain of P100gag-mil abolishes the in vitro autophosphorylation of the protein and the biological properties of the v-mil oncogene of MH2 virusThe conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATPEpidermal growth factor receptor is essential for Toll-like receptor 3 signaling.Autophosphorylation is required for high kinase activity and efficient transformation ability of proteins encoded by host range alleles of v-src.
P2860
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P2860
Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Neither arginine nor histidine ...... he ATP-binding site of p60src.
@en
type
label
Neither arginine nor histidine ...... he ATP-binding site of p60src.
@en
prefLabel
Neither arginine nor histidine ...... he ATP-binding site of p60src.
@en
P2860
P356
P1476
Neither arginine nor histidine ...... he ATP-binding site of p60src.
@en
P2093
P2860
P304
P356
10.1128/MCB.6.3.751
P407
P577
1986-03-01T00:00:00Z