Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH

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Sickle cell disease severity: an introduction.Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.Reactivation of γ-globin in adult β-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing.

P2860

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Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH

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http://www.wikidata.org/entity/Q36913598

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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Original Research: Generation ...... k HPFH and -195 Brazilian HPFH

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Original Research: Generation ...... k HPFH and -195 Brazilian HPFH

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Original Research: Generation ...... k HPFH and -195 Brazilian HPFH

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P1476

Original Research: Generation ...... k HPFH and -195 Brazilian HPFH

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P2093

Carolina A Braghini

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Flavia C Costa

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Halyna Fedosyuk

http://www.w3.org/2001/XMLSchema#string

Kenneth R Peterson

http://www.w3.org/2001/XMLSchema#string

Lesya V Novikova

http://www.w3.org/2001/XMLSchema#string

Matthew P Parker

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Renee Y Neades

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P2860

Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

Erythroid phenotypes associated with KLF1 mutations

Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis

Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor

Mi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic mice

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.

Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.

P304

697-705

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scholarly article

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10.1177/1535370216636724

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241

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R D Winefield

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2016-03-04T00:00:00Z

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26946532

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P921

Hereditary persistence of fetal hemoglobin

P932

4871743

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Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH

about

P2860

P2860

Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH

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P932