Transformation of chicken embryo fibroblasts and tumor induction by the middle T antigen of polyomavirus carried in an avian retroviral vector
about
Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrixMutagenic analysis of the v-crk oncogene: requirement for SH2 and SH3 domains and correlation between increased cellular phosphotyrosine and transformationAssociation of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.Generation of a large library of point mutations in polyoma middle T antigen.Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice.Cooperation of middle and small T antigens of polyomavirus in transformation of established fibroblast and epithelial-like cell lines.Natural biology of polyomavirus middle T antigen.Gene transfer into chicken embryos by retrovirus vectors.Characterization of avian and viral p60src proteins expressed in yeastLessons in signaling and tumorigenesis from polyomavirus middle T antigen.Polyomavirus-mediated transformation: a model of multistep carcinogenesis.Chondrocytes as a specific target of ectopic Fos expression in early developmentp60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells.Polyomavirus middle T-antigen NPTY mutants.Characterization of pp85, a target of oncogenes and growth factor receptorsExpression of 9E3 mRNA is associated with mitogenicity, phosphorylation, and morphological alteration in chicken embryo fibroblasts.Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance.The akt kinase: molecular determinants of oncogenicityPhosphatidylinositol kinase activity associates with viral p60src protein.A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activityRole of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion proteinAssociation of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability.The amino terminus of polyomavirus middle T antigen is required for transformation.Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vectorRecombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro.p56lck protein-tyrosine kinase is cytoskeletal and does not bind to polyomavirus middle T antigen.Genetic determinants of neoplastic diseases induced by a subgroup F avian leukosis virusOverproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector.Interactions between polyomavirus medium T antigen and three cellular proteins of 88, 61, and 37 kilodaltonsLessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.Nondefective spleen necrosis virus-derived vectors define the upper size limit for packaging reticuloendotheliosis virusesHigh-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.Two point mutations in the transmembrane domain of P68gag-ros inactive its transforming activity and cause a delay in membrane association.Generation of recombinant murine retroviral genomes containing the v-src oncogene: isolation of a virus inducing hemangiosarcomas in the brain.Transformation by viral and cellular oncogenes of a mouse BALB/3T3 cell mutant resistant to transformation by chemical carcinogensHuman endothelial cells expressing polyoma middle T induce tumors.High-level expression of human c-jun gene causes cellular transformation of chicken embryo fibroblasts.Association of the polyomavirus middle-T antigen with c-yes protein
P2860
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P2860
Transformation of chicken embryo fibroblasts and tumor induction by the middle T antigen of polyomavirus carried in an avian retroviral vector
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Transformation of chicken embr ...... in an avian retroviral vector
@en
type
label
Transformation of chicken embr ...... in an avian retroviral vector
@en
prefLabel
Transformation of chicken embr ...... in an avian retroviral vector
@en
P2093
P2860
P356
P1476
Transformation of chicken embr ...... in an avian retroviral vector
@en
P2093
H Hanafusa
M Harbison
S Kornbluth
P2860
P304
P356
10.1128/MCB.6.5.1545
P407
P577
1986-05-01T00:00:00Z