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Chirality and pharmacokinetics: an area of neglected dimensionality?

Chirality and pharmacokinetics: an area of neglected dimensionality?

http://www.wikidata.org/entity/Q36914170

about

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein Using biological performance similarity to inform disaccharide library design.Chiral analytical method development of liquiritigenin with application to a pharmacokinetic study Chiral analytical method development and application to pre-clinical pharmacokinetics of pinocembrin.Pharmacologically active compounds in the environment and their chirality.Chemodiversity and molecular plasticity: recognition processes as explored by property spaces.Chirality and anaesthetic drugs: A review and an update.Isolation and evaluation of the enantiospecific antitubercular activity of a novel triazole compound.Transcriptome-enabled discovery and functional characterization of enzymes related to (2S)-pinocembrin biosynthesis from Ornithogalum caudatum and their application for metabolic engineering Characterizing QT interval prolongation in early clinical development: a case study with methadone.Synthesis, molecular modeling, and biological evaluation of novel chiral thiosemicarbazone derivatives as potent anticancer agents.Pharmacokinetics of nateglinide enantiomers and their metabolites in Goto-Kakizaki rats, a model for type 2 diabetes mellitus.A clinical and microbiological study on the enantiomers of delmopinol.Stereoselective formation and metabolism of 20(S)-protopanaxadiol ocotillol type epimers in vivo and in vitro.Reliable HPLC separation, vibrational circular dichroism spectra, and absolute configurations of isoborneol enantiomers.Bifunctional catalysis in the stereocontrolled synthesis of tetrahydro-1,2-oxazines.Pharmacokinetic comparisons of S-oxiracetam and R-oxiracetam in beagle dogs.

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P2860

Chirality and pharmacokinetics: an area of neglected dimensionality?

http://www.wikidata.org/entity/Q36914170

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Chirality and pharmacokinetics: an area of neglected dimensionality?

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type

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Chirality and pharmacokinetics: an area of neglected dimensionality?

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Chirality and pharmacokinetics: an area of neglected dimensionality?

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DMDI.2007.22.2-3.79

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Drug Metabolism and Drug Interactions

P1476

Chirality and pharmacokinetics: an area of neglected dimensionality?

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P2093

Andrew J Hutt

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P2860

Absolute configuration of the major metabolite of 5,5-diphenylhydantoin, 5-(4'-hydroxyphenyl)-5-phenylhydantoin

Stereoselective transport of baclofen across the blood-brain barrier in rats as determined by the unit impulse response methodology.

Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology.

Stereospecific determination, chiral inversion in vitro and pharmacokinetics in humans of the enantiomers of thalidomide.

Separation of enantiomers: needs, challenges, perspectives.

Interpretation of experiments on metabolic processes, using isotopic tracer elements.

Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites.

Diastereoisomerism, contact points, and chiral selectivity: a four-site saga.

Influence of age on the enantiomeric disposition of ibuprofen in healthy volunteers

Enantiomeric disposition of inhaled, intravenous and oral racemic-salbutamol in man--no evidence of enantioselective lung metabolism

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79-112

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scholarly article

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10.1515/DMDI.2007.22.2-3.79

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2-3

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22

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2007-01-01T00:00:00Z

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17708062

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