IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ - Wikidata - wikimedia - TriplyDB

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

http://www.wikidata.org/entity/Q36914486

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Resolution of Inflammation: What Controls Its Onset?Inflammasome/IL-1β Responses to Streptococcal Pathogens The therapeutic value of targeting inflammation in gastrointestinal cancers CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex Inflammation meets cancer, with NF-κB as the matchmaker An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review.The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.Essential role of interleukin-1 signaling in host defenses against group B streptococcus.Transcriptome kinetics of circulating neutrophils during human experimental endotoxemia.Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages.Characterization of a novel mouse model with genetic deletion of CD177 Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation.NF-κB and STAT3 - key players in liver inflammation and cancer Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model.Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.Disordered haematopoiesis and athero-thrombosis.NF-κB activation in myeloid cells mediates ventilator-induced lung injury.Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer.NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases Obesity, inflammation, and liver cancer.JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation.IL-1β is an innate immune sensor of microbial proteolysis.The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.Regulation of NF-κB by ubiquitination and degradation of the IκBs.NF-κB and the link between inflammation and cancer.Emerging roles of Lys63-linked polyubiquitylation in immune responses.Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment.Targeting Inflammation in Cancer Prevention and Therapy.Fracture initiates systemic inflammatory response syndrome through recruiting polymorphonuclear leucocytes.Group A streptococcal M protein activates the NLRP3 inflammasome.Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.Revisiting the protective and pathogenic roles of neutrophils: Ly-6G is key!

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IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

http://www.wikidata.org/entity/Q36914486

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

IL-1β-driven neutrophilia pres ...... the absence of the kinase IKKβ

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IL-1β-driven neutrophilia pres ...... the absence of the kinase IKKβ

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IL-1β-driven neutrophilia pres ...... the absence of the kinase IKKβ

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Nature Immunology

P1476

IL-1β-driven neutrophilia pres ...... the absence of the kinase IKKβ

@en

P2093

Anjuli M Timmer

http://www.w3.org/2001/XMLSchema#string

Chih-Yuan Lee

http://www.w3.org/2001/XMLSchema#string

Guann-Yi Yu

http://www.w3.org/2001/XMLSchema#string

Irving L Weissman

http://www.w3.org/2001/XMLSchema#string

Thiha Aung

http://www.w3.org/2001/XMLSchema#string

Thomas Enzler

http://www.w3.org/2001/XMLSchema#string

Ting-Yu Lai

http://www.w3.org/2001/XMLSchema#string

Ursula Sinzig

http://www.w3.org/2001/XMLSchema#string

Vladislav Temkin

http://www.w3.org/2001/XMLSchema#string

P2860

Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8

How neutrophils kill microbes

Neutrophil extracellular traps kill bacteria

Pathogen recognition and innate immunity

Regulation and function of IKK and IKK-related kinases

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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144-150

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scholarly article

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10.1038/NI.1976

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2

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12

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Liang-Chuan Lai

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2010-12-19T00:00:00Z

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49694636

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1022516418

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21170027

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3677078

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