Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
about
Sumoylation and transcription regulation at nuclear poresNuclear pore proteins and the control of genome functionsDefective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport.Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsThe Nup153-Nup50 protein interface and its role in nuclear import.In vivo analysis of human nucleoporin repeat domain interactions.Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo.SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis.The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function.An essential role of small ubiquitin-like modifier (SUMO)-specific Protease 2 in myostatin expression and myogenesis.Starting and stopping SUMOylation. What regulates the regulator?Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair.The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts.Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex.HOXA repression is mediated by nucleoporin Nup93 assisted by its interactors Nup188 and Nup205.Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis.Nup153 and Nup50 promote recruitment of 53BP1 to DNA repair foci by antagonizing BRCA1-dependent events.SUMO-Mediated Regulation of Nuclear Functions and Signaling ProcessesThe SUMO-specific isopeptidase SENP2 is targeted to intracellular membranes via a predicted N-terminal amphipathic α-helix
P2860
Q26999229-D759B98E-D87F-48D4-9A0D-0A1CDEE85ADFQ28085670-55034FE4-585B-4B39-8F3F-24A902A7FA95Q30416354-49340187-AE7F-4227-B70C-2FC0626669ADQ36165625-6210DE56-FC3E-4ADE-9445-60275496208AQ36385778-F4A1F526-3212-486A-9AFD-7EED021C3BD0Q36758440-0D7D791C-189D-4E4F-8BA2-FB6DB5BC53CBQ37178230-352C7FF2-1591-41F4-B639-E2DADA573E99Q37306184-40603DB2-329A-42C7-8357-6BDC697179CDQ37416495-3C6E5057-39A1-4006-B257-9A6480E08F0FQ37563422-BB353FF9-DF6A-4E76-A2F6-C9E120307530Q38118140-509A0728-E1BB-4735-BAB8-83C6D16AA18DQ38747471-CAAD5311-47D0-4B77-8CE5-039590193E6BQ38780863-6C18A7CB-EA33-42C7-A3A3-CB4E6C2753FFQ41978445-38D17A58-BB62-46B8-8D0C-96A6B54DCB0FQ42359419-0529F676-9165-428B-834E-59B115459612Q47263437-C2DA5269-D0BB-475F-8D8C-36AFA299D46BQ48333916-E32EC66E-EF48-4C5D-95D6-11246E7A7899Q58803049-B058F1EB-FB80-44C6-9BCB-D9A0131B92E7Q58806147-4BA883CE-7B25-4854-B14D-989A9640E0F5
P2860
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
@en
type
label
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
@en
prefLabel
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
@en
P2093
P2860
P356
P1433
P1476
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.
@en
P2093
Katharine S Ullman
Kin-Hoe Chow
Suzanne Elgort
P2860
P304
P356
10.4161/NUCL.20822
P50
P577
2012-06-12T00:00:00Z