Class II HLA interactions modulate genetic risk for multiple sclerosis. - Wikidata - wikimedia - TriplyDB

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

http://www.wikidata.org/entity/Q36920509

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Neuroinflammation - using big data to inform clinical practice.The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic Opportunities.The MHC locus and genetic susceptibility to autoimmune and infectious diseases.Meta-Analysis of Differential Connectivity in Gene Co-Expression Networks in Multiple Sclerosis.Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis Linking Genotype to Clinical Phenotype in Multiple Sclerosis: In Search of the Holy Grail.Computational modeling of brain pathologies: the case of multiple sclerosis.Protective alleles and modifier variants in human health and disease.Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.Epigenetic research in multiple sclerosis: progress, challenges, and opportunities.Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma.Integrative Genetic and Epigenetic Analysis Uncovers Regulatory Mechanisms of Autoimmune Disease.Genetics of autoimmune diseases: perspectives from genome-wide association studies.From genetic associations to functional studies in multiple sclerosis.Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study.Role of Oligodendrocyte Dysfunction in Demyelination, Remyelination and Neurodegeneration in Multiple Sclerosis.A multi-hit hypothesis of bullous pemphigoid and associated neurological disease: Is HLA-DQB1*03:01, a potential link between immune privileged antigen exposure and epitope spreading?Axonal transport deficits in multiple sclerosis: spiraling into the abyss.Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.Molecular genetic contributions to self-rated health.Investigating multiple sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci.The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.The immunogenetics of neurological disease.Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.An insight about genomic susceptibility & multiple sclerosis.Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship.Western lifestyle and immunopathology of multiple sclerosis.Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.Autoimmune Subepidermal Bullous Diseases of the Skin and Mucosae: Clinical Features, Diagnosis, and Management.miR-155 Dysregulation and Therapeutic Intervention in Multiple Sclerosis.Human leucocyte antigen (HLA) class I and II typing in Belgian multiple sclerosis patients.High resolution HLA analysis reveals independent class I haplotypes and amino-acid motifs protective for multiple sclerosis.Genetic basis for relapse rate in multiple sclerosis: Association with LRP2 genetic variation.Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.A population genetic interpretation of GWAS findings for human quantitative traits.Variant of EOMES Associated with Increasing Risk in Chinese Patients with Relapsing-remitting Multiple Sclerosis.HLA variation and disease.Genome-wide association studies of multiple sclerosis.

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P2860

Class II HLA interactions modulate genetic risk for multiple sclerosis.

http://www.wikidata.org/entity/Q36920509

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2015年论文

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2015年论文

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name

Class II HLA interactions modulate genetic risk for multiple sclerosis.

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Class II HLA interactions modulate genetic risk for multiple sclerosis.

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Class II HLA interactions modulate genetic risk for multiple sclerosis.

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Nature Genetics

P1476

Class II HLA interactions modulate genetic risk for multiple sclerosis.

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P2093

Adrian J Ivinson

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Annette Oturai

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Ashley H Beecham

http://www.w3.org/2001/XMLSchema#string

Bernhard Hemmer

http://www.w3.org/2001/XMLSchema#string

Bertrand Fontaine

http://www.w3.org/2001/XMLSchema#string

Bruce Taylor

http://www.w3.org/2001/XMLSchema#string

Chris C A Spencer

http://www.w3.org/2001/XMLSchema#string

Christiane Graetz

http://www.w3.org/2001/XMLSchema#string

David Booth

http://www.w3.org/2001/XMLSchema#string

Dionysia K Xifara

http://www.w3.org/2001/XMLSchema#string

P2860

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects

Finding the missing heritability of complex diseases

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

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1107-1113

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10.1038/NG.3395

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10

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47

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Alastair Compston

David A. Hafler

Margaret A. Pericak-Vance

Lars Alfredsson

Juliane Winkelmann

Jeffrey C Barrett

Calliope A. Dendrou

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2015-09-07T00:00:00Z

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1052877676

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26343388

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multiple sclerosis

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4874245

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