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Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

http://www.wikidata.org/entity/Q36926215

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Biomedical and clinical promises of human pluripotent stem cells for neurological disorders Rapid single-step induction of functional neurons from human pluripotent stem cells Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research Using Patient-Derived Induced Pluripotent Stem Cells to Model and Treat Epilepsies Investigation of Rett syndrome using pluripotent stem cells iPSC-derived neurons as a higher-throughput readout for autism: promises and pitfalls Stem cell imaging: from bench to bedside Pluripotent stem cells in regenerative medicine: challenges and recent progress Concise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion Building blocks of the cerebral cortex: from development to the dish Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology Cell-based screening: extracting meaning from complex data.Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells From "directed differentiation" to "neuronal induction": modeling neuropsychiatric disease Interneuron Progenitor Transplantation to Treat CNS Dysfunction Utility of Induced Pluripotent Stem Cells for the Study and Treatment of Genetic Diseases: Focus on Childhood Neurological Disorders Overcoming the hurdles for a reproducible generation of human functionally mature reprogrammed neurons Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair Stem cell therapy for Alzheimer's disease and related disorders: current status and future perspectives Evolution of Osteocrin as an activity-regulated factor in the primate brain Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System Toward pluripotency by reprogramming: mechanisms and application Potential of GABA-ergic cell therapy for schizophrenia, neuropathic pain, and Alzheimer's and Parkinson's diseases.Remote control of induced dopaminergic neurons in parkinsonian rats.Interneurons from embryonic development to cell-based therapy.Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.Stem cell models of Alzheimer's disease: progress and challenges.Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells.Human fetal brain-derived neural stem/progenitor cells grafted into the adult epileptic brain restrain seizures in rat models of temporal lobe epilepsy.WONOEP appraisal: new genetic approaches to study epilepsy The complexity of the calretinin-expressing progenitors in the human cerebral cortex.Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.Flow cytometry protocols for surface and intracellular antigen analyses of neural cell types Moving stem cells to the clinic: potential and limitations for brain repair Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.

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Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

http://www.wikidata.org/entity/Q36926215

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J.STEM.2013.04.008

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Directed differentiation and f ...... rom human embryonic stem cells

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Adam Goulburn

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Andrew G Elefanty

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Asif M Maroof

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Becky Liu

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Edouard G Stanley

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Florian T Merkle

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Hans Ruedi Widmer

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Jennifer A Tyson

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Kevin Eggan

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Peter A Goldstein

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P2860

Rethinking schizophrenia

Origin of GABAergic neurons in the human neocortex

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Modelling schizophrenia using human induced pluripotent stem cells.

Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines

Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes

Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon

Origins of cortical interneuron subtypes

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells

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10.1016/J.STEM.2013.04.008

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