How can we improve the pre-clinical development of drugs for stroke?
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The need for randomization in animal trials: an overview of systematic reviewsCan animal models of disease reliably inform human studies?Publication bias in reports of animal stroke studies leads to major overstatement of efficacyA preclinical physiological assay to test modulation of knee joint pain in the spinal cord: effects of oxycodone and naproxenWhere Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and StrokeThe methodological quality of animal research in critical care: the public face of scienceA call for transparent reporting to optimize the predictive value of preclinical researchSystematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and MetabolismPublication and other reporting biases in cognitive sciences: detection, prevalence, and prevention.Reproducibility of results in preclinical studies: a perspective from the bone fieldSystematic reviews of animal models: methodology versus epistemology.Neuroprotective Strategies after Neonatal Hypoxic Ischemic EncephalopathyQuality of Animal Experiments in Anti-Angiogenic Cancer Drug Development--A Systematic ReviewRefinement of Experimental Design and Conduct in Laboratory Animal ResearchCritical appraisal of studies using laboratory animal modelsOxidative Stress and the Use of Antioxidants in StrokeNeuroprotection after stroke by targeting NOX4 as a source of oxidative stressEffect of endothelin receptor antagonists on clinically relevant outcomes after experimental subarachnoid hemorrhage: a systematic review and meta-analysisStem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studiesDerivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in ratsXenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled TrialThe effects of probiotic supplementation on experimental acute pancreatitis: a systematic review and meta-analysisNonindustry-sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysisSome salt with your statin, professor?Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerationsAuthorization of Animal Experiments Is Based on Confidence Rather than Evidence of Scientific RigorPain and Laboratory Animals: Publication Practices for Better Data Reproducibility and Better Animal WelfareMinimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experimentsA concerted appeal for international cooperation in preclinical stroke researchUpdate of the stroke therapy academic industry roundtable preclinical recommendationsMouse models to study the effect of cardiovascular risk factors on brain structure and cognitionStructured evaluation of rodent behavioral tests used in drug discovery research.Evaluation of animal models of neurobehavioral disorders.Preclinical research in Rett syndrome: setting the foundation for translational success.Assessing post-stroke behavior in mouse models of focal ischemia.Transplantation of cryopreserved human umbilical cord blood mononuclear cells does not induce sustained recovery after experimental stroke in spontaneously hypertensive rats.Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy for a novel 5HT(1A) agonist in rat models of ischaemic stroke.Where will the next generation of stroke treatments come from?Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal researchExperimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis.
P2860
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P2860
How can we improve the pre-clinical development of drugs for stroke?
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
How can we improve the pre-clinical development of drugs for stroke?
@en
type
label
How can we improve the pre-clinical development of drugs for stroke?
@en
prefLabel
How can we improve the pre-clinical development of drugs for stroke?
@en
P50
P1476
How can we improve the pre-clinical development of drugs for stroke?
@en
P2093
H Bart van der Worp
P304
P356
10.1016/J.TINS.2007.06.009
P577
2007-08-31T00:00:00Z