The Mr 140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring
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Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia.Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia.The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans.Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.The 9 + 2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motilityLocalization of calmodulin and dynein light chain LC8 in flagellar radial spokesGenetic analysis of the cytoplasmic dynein subunit families.Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum.Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysisCRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for SpermiogenesisIC138 is a WD-repeat dynein intermediate chain required for light chain assembly and regulation of flagellar bendingTCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcriptsIC138 defines a subdomain at the base of the I1 dynein that regulates microtubule sliding and flagellar motilityDistinct roles of 1alpha and 1beta heavy chains of the inner arm dynein I1 of Chlamydomonas flagella.bop5 Mutations reveal new roles for the IC138 phosphoprotein in the regulation of flagellar motility and asymmetric waveformsThe MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility.CMF22 is a broadly conserved axonemal protein and is required for propulsive motility in Trypanosoma brucei.Changes in the abundance and distribution of conserved centrosomal, cytoskeletal and ciliary proteins during spermiogenesis in Marsilea vestita.Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression.Identification and characterization of endonuclein binding proteins: evidence of modulatory effects on signal transduction and chaperone activityDimeric novel HSP40 is incorporated into the radial spoke complex during the assembly process in flagellaOda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase.Insights into the structural organization of the I1 inner arm dynein from a domain analysis of the 1beta dynein heavy chain.A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex.Molecular map of the Chlamydomonas reinhardtii nuclear genomeA novel ankyrin-repeat protein interacts with the regulatory proteins of inner arm dynein f (I1) of Chlamydomonas reinhardtiiAn axonemal PP2A B-subunit is required for PP2A localization and flagellar motility.Chlamydomonas axonemal dynein assembly locus ODA8 encodes a conserved flagellar protein needed for cytoplasmic maturation of outer dynein arm complexesBuilding blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella.A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures.Flagellar radial spoke protein 2 is a calmodulin binding protein required for motility in Chlamydomonas reinhardtii.DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DCThe ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking.Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein.Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body.Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella.Keeping an eye on I1: I1 dynein as a model for flagellar dynein assembly and regulation.LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly.The Chlamydomonas IDA7 locus encodes a 140-kDa dynein intermediate chain required to assemble the I1 inner arm complex.
P2860
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P2860
The Mr 140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The Mr 140,000 intermediate ch ...... icated in dynein arm anchoring
@en
type
label
The Mr 140,000 intermediate ch ...... icated in dynein arm anchoring
@en
prefLabel
The Mr 140,000 intermediate ch ...... icated in dynein arm anchoring
@en
P2860
P356
P1476
The Mr 140,000 intermediate ch ...... icated in dynein arm anchoring
@en
P2860
P304
P356
10.1091/MBC.9.12.3335
P577
1998-12-01T00:00:00Z