Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways
about
Cell-surface receptors transactivation mediated by g protein-coupled receptorsPhosphatidylserine exposure is required for ADAM17 sheddase functionVisualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.EGF receptor ligands: recent advancesPI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune PolarizationPreferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.A1 adenosine receptor-stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation.Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domainHigh-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neuronsReduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor ResistanceGrowth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases.Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation.Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding.Multiple non-catalytic ADAMs are novel integrin α4 ligands.Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17.Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway.Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.
P2860
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P2860
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways
@en
type
label
Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways
@en
prefLabel
Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways
@en
P2093
P2860
P356
P1476
Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways
@en
P2093
Andreas Herrlich
David E Root
Efrain Cermeno
George W Bell
Michelle Dang
Miles A Miller
Monika Hartmann
Nicole Armbruster
P2860
P304
P356
10.1073/PNAS.1307478110
P407
P577
2013-05-29T00:00:00Z