HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function - Wikidata - wikimedia - TriplyDB

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

http://www.wikidata.org/entity/Q36932447

about

Coevolution of MHC genes (LMP/TAP/class Ia, NKT-class Ib, NKp30-B7H6): lessons from cold-blooded vertebrates Considerations for combined immune checkpoint modulation and radiation treatment.Structure and cancer immunotherapy of the B7 family member B7x A New B7:CD28 Family Checkpoint Target for Cancer Immunotherapy: HHLA2.Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein.Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family.Emerging targets in cancer immunotherapy: beyond CTLA-4 and PD-1.HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer.The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy.Combination cancer immunotherapies tailored to the tumour microenvironment.The expanding repertoire of targets for immune checkpoint inhibition in bladder cancer: What lies beneath the tip of the iceberg, PD-L1.Immunotherapy for advanced melanoma: future directions.The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3.New B7 Family Checkpoints in Human Cancers.HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status.HHLA2 and TMIGD2: new immunotherapeutic targets of the B7 and CD28 families.Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells.B7-H3 in tumors: friend or foe for tumor immunity?Wide expression and significance of alternative immune checkpoint molecules, B7x and HHLA2, in PD-L1 negative human lung cancers.Phenotype and tissue distribution of CD28H+ immune cell subsets.TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer.Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma.The association of human endogenous retrovirus-H long terminal repeat-associating protein 2 (HHLA2) expression with gastric cancer prognosis.Not All Immune Checkpoints Are Created Equal

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HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

http://www.wikidata.org/entity/Q36932447

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

@en

type

label

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

@en

prefLabel

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

@en

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PNAS.1303524110

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Proceedings of the National Academy of Sciences of the United States of America

P1476

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

@en

P2093

Aimin Zhao

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Anjana Ray

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Hyungjun Jeon

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Jordan M Chinai

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Kaya Ghosh

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Kim C Ohaegbulam

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Lisa Scandiuzzi

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Matthew D Scharff

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Ruihua Zhao

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Susan Buhl

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P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

The PD-1 pathway in tolerance and autoimmunity

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

B7x: a widely expressed B7 family member that inhibits T cell activation

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10.1073/PNAS.1303524110

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110

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