The dynamic regulation of NAD metabolism in mitochondria.
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New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncologyReview: can diet influence the selective advantage of mitochondrial DNA haplotypes?Bioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening.Detection of cerebral NAD(+) by in vivo (1)H NMR spectroscopy.Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion.The metabolic profile of a rat model of chronic kidney disease.Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortexDNA damage related crosstalk between the nucleus and mitochondria.SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts.Ketone bodies as signaling metabolites.Electroosmotic perfusion of tissue: sampling the extracellular space and quantitative assessment of membrane-bound enzyme activity in organotypic hippocampal slice cultures.Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during agingNAMPT regulates mitochondria biogenesis via NAD metabolism and calcium binding proteins during skeletal muscle contraction.Determining the origins of superoxide and hydrogen peroxide in the mammalian NADH:ubiquinone oxidoreductase.The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms.Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP.Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondriaAge affects the contraction-induced mitochondrial redox response in skeletal muscle.In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences.Modelling and analysis of the feeding regimen induced entrainment of hepatocyte circadian oscillators using petri netsβ-hydroxybutyrate: much more than a metaboliteSIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice.Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo.An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate SynthesisCyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging BoneSalvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post-hypoxic cardiomyocytes.Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.Metabolic Reprogramming of Stem Cell Epigenetics.Nampt is required for long-term depression and the function of GluN2B subunit-containing NMDA receptorsGlobal Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic OptimumEnhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1).CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cellsQuantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulationThe importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing.SIRT6 suppresses mitochondrial defects and cell death via the NF-κB pathway in myocardial hypoxia/reoxygenation induced injuryImprovement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet.Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography.Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.Nutrient and Metabolic Sensing in T Cell Responses.
P2860
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P2860
The dynamic regulation of NAD metabolism in mitochondria.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The dynamic regulation of NAD metabolism in mitochondria.
@en
type
label
The dynamic regulation of NAD metabolism in mitochondria.
@en
prefLabel
The dynamic regulation of NAD metabolism in mitochondria.
@en
P2860
P1476
The dynamic regulation of NAD metabolism in mitochondria.
@en
P2093
Liana Roberts Stein
Shin-ichiro Imai
P2860
P304
P356
10.1016/J.TEM.2012.06.005
P577
2012-07-21T00:00:00Z