Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes
about
GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus.Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesinExpression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase BNegative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitroInsulin-regulated aminopeptidase marks an antigen-stimulated recycling compartment in mast cellsDirect interaction of Rab4 with syntaxin 4TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recyclingLipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation.GLUT4--at the cross roads between membrane trafficking and signal transduction.The GLUT4 codeInsulin-regulated release from the endosomal recycling compartment is regulated by budding of specialized vesicles.VAMP3 null mice display normal constitutive, insulin- and exercise-regulated vesicle trafficking.G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane.ADP-ribosylation factor 6 delineates separate pathways used by endothelin 1 and insulin for stimulating glucose uptake in 3T3-L1 adipocytes.Signaling pathways in insulin action: molecular targets of insulin resistanceVesicle-associated membrane protein 2 (VAMP2) but Not VAMP3 mediates cAMP-stimulated trafficking of the renal Na+-K+-2Cl- co-transporter NKCC2 in thick ascending limbsVAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts.Insulin recruits GLUT4 from specialized VAMP2-carrying vesicles as well as from the dynamic endosomal/trans-Golgi network in rat adipocytesCharacterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear falloutPush/pull mechanisms of GLUT4 traffic in muscle cells.GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomesVesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE.Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.SNARE proteins underpin insulin-regulated GLUT4 traffic.Naphthalenemethyl ester derivative of dihydroxyhydrocinnamic acid, a component of cinnamon, increases glucose disposal by enhancing translocation of glucose transporter 4.GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps.Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes.Identification of further important residues within the Glut4 carboxy-terminal tail which regulate subcellular trafficking.Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes.Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes.Characterization of GLUT4-containing vesicles in 3T3-L1 adipocytes by total internal reflection fluorescence microscopy.Effects of contraction on localization of GLUT4 and v-SNARE isoforms in rat skeletal muscle.Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes.
P2860
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P2860
Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Differential regulation of sec ...... sporter 4 in 3T3-L1 adipocytes
@en
type
label
Differential regulation of sec ...... sporter 4 in 3T3-L1 adipocytes
@en
prefLabel
Differential regulation of sec ...... sporter 4 in 3T3-L1 adipocytes
@en
P2093
P2860
P356
P1476
Differential regulation of sec ...... sporter 4 in 3T3-L1 adipocytes
@en
P2093
C A Millar
G R Hickson
P2860
P304
P356
10.1091/MBC.10.11.3675
P577
1999-11-01T00:00:00Z