Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
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Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryApplication of metabolomics in drug resistant breast cancer researchAlternative fuels for cancer cellsTumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolismA joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer.REG3β modifies cell tumor function by impairing extracellular vesicle uptake.Weight Loss Reversed Obesity-Induced HGF/c-Met Pathway and Basal-Like Breast Cancer ProgressionStroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitorsA joint analysis of metabolomics and genetics of breast cancer.Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice.Benign breast tissue composition in breast cancer patients: association with risk factors, clinical variables, and gene expressionNutrition and metabolic correlates of obesity and inflammation: clinical considerations.Metabolic Signatures of Human Breast Cancer.Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signalingOsteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancerHuman lymphatic endothelial cells contribute to epithelial ovarian carcinoma metastasis by promoting lymphangiogenesis and tumour cell invasion.cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancerMetabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness.Triggering the landslide: The tumor-promotional effects of myofibroblastsObesity, metabolism and the microenvironment: Links to cancerOncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.A dual sensor for real-time monitoring of glucose and oxygen.Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer.Plasma metabolomic analysis of human hepatocellular carcinoma: Diagnostic and therapeutic studyProlactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment.Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ.Analytical protocols based on LC-MS, GC-MS and CE-MS for nontargeted metabolomics of biological tissues.Introduction to the molecular basis of cancer metabolism and the Warburg effect.Cancer-Associated Fibroblasts Autophagy Enhances Progression of Triple-Negative Breast Cancer Cells.Transglutaminase 2 in cancer.c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma.Role of tumor microenvironment in triple-negative breast cancer and its prognostic significanceDifferences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer.Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate.The metabolic interaction of cancer cells and fibroblasts - coupling between NAD(P)H and FAD, intracellular pH and hydrogen peroxide.Cancer metabolism: new validated targets for drug discovery.18F-fluorodeoxyglucose uptake predicts MET expression in lung adenocarcinoma.Extracellular vesicles as mediators of the progression and chemoresistance of pancreatic cancer and their potential clinical applications.Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition.Influence of the Tumor Microenvironment on Cancer Cells Metabolic Reprogramming.
P2860
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P2860
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
@en
type
label
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
@en
prefLabel
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
@en
P2093
P2860
P50
P1476
Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer
@en
P2093
Alex J Freemerman
Erick Romàn-Pèrez
Lindsay J Lang
Liza Makowski
Melissa A Troester
Patricia Casbas-Hernandez
P2860
P304
P356
10.1158/1078-0432.CCR-12-2123
P407
P577
2012-12-12T00:00:00Z