A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.
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Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists.Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probesRenal intercalated cells sense and mediate inflammation via the P2Y14 receptor.John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y ReceptorsUDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.Medicinal chemistry of adenosine, P2Y and P2X receptors.Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor.From quiescence to senescence.UDP-glucose promotes neutrophil recruitment in the lung.Novel vasocontractile role of the P2Y₁₄ receptor: characterization of its signalling in porcine isolated pancreatic arteries.Nucleoside 5'-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation.Purinergic signalling and immune cells.A critical look at the function of the P2Y11 receptor.The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury.Empowering human cardiac progenitor cells by P2Y14 nucleotide receptor overexpression.UDP-sugars activate P2Y14 receptors to mediate vasoconstriction of the porcine coronary artery.P2Y14 receptor activation decreases interleukin-6 production and glioma GL261 cell proliferation in microglial transwell cultures.Breakthrough in GPCR Crystallography and Its Impact on Computer-Aided Drug Design.Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling.Purinergic Regulation of Neutrophil Function.
P2860
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P2860
A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A selective high-affinity anta ...... emotaxis of human neutrophils.
@en
type
label
A selective high-affinity anta ...... emotaxis of human neutrophils.
@en
prefLabel
A selective high-affinity anta ...... emotaxis of human neutrophils.
@en
P2093
P2860
P356
P1476
A selective high-affinity anta ...... hemotaxis of human neutrophils
@en
P2093
Christopher B Ball
Eduardo R Lazarowski
Juliana I Sesma
Matthew O Barrett
P Suresh Jayasekara
T Kendall Harden
P2860
P356
10.1124/MOL.113.085654
P577
2013-04-16T00:00:00Z