Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice. - Wikidata - wikimedia - TriplyDB

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

http://www.wikidata.org/entity/Q36936058

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Animal Models for HIV Cure Research Studies of retroviral infection in humanized mice New generation humanized mice for virus research: comparative aspects and future prospects T-Regulatory Cells and Vaccination "Pay Attention and Do Not Neglect Them": Lessons from HIV and Cancer Vaccine Trials Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice HIV Replication Is Not Controlled by CD8+ T Cells during the Acute Phase of the Infection in Humanized Mice In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.A Multiple siRNA-Based Anti-HIV/SHIV Microbicide Shows Protection in Both In Vitro and In Vivo Models Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice Human T-Cell Development and Thymic Egress: An Infectious Disease Perspective PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads.An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice Hypogammaglobulinemia in BLT humanized mice--an animal model of primary antibody deficiency.Study of viral pathogenesis in humanized mice Evaluation of the efficiency of human immune system reconstitution in NSG mice and NSG mice containing a human HLA.A2 transgene using hematopoietic stem cells purified from different sources.IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection In vivo analysis of Nef's role in HIV-1 replication, systemic T cell activation and CD4(+) T cell loss.BLT humanized mice as a small animal model of HIV infection.In vivo platforms for analysis of HIV persistence and eradication.Pulmonary Tuberculosis in Humanized Mice Infected with HIV-1 HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication Adoptive transfer of lymphocytes isolated from simian immunodeficiency virus SIVmac239Δnef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients.Humanized mice for the study of infectious diseases.HIV-specific CD8⁺ T-cell immunity in humanized bone marrow-liver-thymus mice Recent advances in humanized mice: accelerating the development of an HIV vaccine Overcoming current limitations in humanized mouse research Humoral immunity in humanized mice: a work in progress.Human immune responses and potential for vaccine assessment in humanized mice.Infectious diseases in humanized mice.Humanized mice for HIV and AIDS research.HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/- (RAG1-Hu) and BLT Mice.Targeting type I interferon-mediated activation restores immune function in chronic HIV infection.In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies.Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice.Mice engrafted with human hematopoietic stem cells support a human myeloid cell inflammatory response in vivo.Visualizing the Behavior of HIV-Infected T Cells In Vivo Using Multiphoton Intravital Microscopy.Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.Roadblocks to translational challenges on viral pathogenesis.Human Immune System Mice for the Study of Human Immunodeficiency Virus-Type 1 Infection of the Central Nervous System.

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Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

http://www.wikidata.org/entity/Q36936058

description

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2012年论文

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2012年论文

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2012年论文

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name

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

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type

label

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

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prefLabel

Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

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SCITRANSLMED.3003984

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Science Translational Medicine

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Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.

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Adrianne D Gladden

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Andrew D Luster

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Andrew M Tager

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Christian L Boutwell

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Daniel C No

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Elizabeth F Mellors

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Laura Battis

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Lena Fadda

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P2860

Common genetic variation and the control of HIV-1 in humans

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

Viral evolution and escape during acute HIV-1 infection

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24.

Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.

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