In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.
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Immunoregulatory functions of immune complexes in vaccine and therapyTherapeutic implications of autoantibodies in rheumatoid arthritisTargeting the Fc receptor in autoimmune diseaseMonocyte recruitment by HLA IgG-activated endothelium: the relationship between IgG subclass and FcγRIIa polymorphisms.Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor InteractionsCrystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodiesImmune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesImmunoglobulin M antiplatelet autoantibodies from mice immunized with rat platelets induce thrombocytopenia and platelet function impairment.Glycans are a novel biomarker of chronological and biological ages.Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence.The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis.Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.Fc-glycosylation of IgG1 is modulated by B-cell stimuli.EndoS reduces the pathogenicity of anti-mCOL7 IgG through reduced binding of immune complexes to neutrophils.IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.Microscale purification of antigen-specific antibodies.CP40 from Corynebacterium pseudotuberculosis is an endo-β-N-acetylglucosaminidase.Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine componentRequirement for innate immunity and CD90⁺ NK1.1⁻ lymphocytes to treat established melanoma with chemo-immunotherapy.Enzymatic deglycosylation converts pathogenic neuromyelitis optica anti-aquaporin-4 immunoglobulin G into therapeutic antibody.General mechanism for modulating immunoglobulin effector function.Dominant suppression of inflammation by glycan-hydrolyzed IgGTherapeutic potential of deglycosylated antibodies.Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisitaEndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein.Liquid-liquid diffusion crystallization improves the X-ray diffraction of EndoS, an endo-β-N-acetylglucosaminidase from Streptococcus pyogenes with activity on human IgGIntravenous immunoglobulins in systemic lupus erythematosus: from the bench to the bedside.Complex genetic regulation of protein glycosylation.Structure and function of immunoglobulinsChemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa.Evolutionary-developmental perspectives on immune system interactions among the pregnant woman, placenta, and fetus, and responses to sexually transmitted infectious agents.Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond.The carbohydrate switch between pathogenic and immunosuppressive antigen-specific antibodies.Targeting B cells and autoantibodies in the therapy of autoimmune diseases.Type I and type II Fc receptors regulate innate and adaptive immunity.Mechanisms of tissue damage in arthritis.Fcγ receptor pathways during active and passive immunization.Discovering potential drug-targets for personalized treatment of autoimmune disorders - what we learn from epidermolysis bullosa acquisita.In vivo enzymatic modulation of IgG antibodies prevents immune complex-dependent skin injury.
P2860
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P2860
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
In vivo enzymatic modulation o ...... IgG subclass-dependent manner.
@en
type
label
In vivo enzymatic modulation o ...... IgG subclass-dependent manner.
@en
prefLabel
In vivo enzymatic modulation o ...... IgG subclass-dependent manner.
@en
P2093
P2860
P356
P1476
In vivo enzymatic modulation o ...... IgG subclass-dependent manner.
@en
P2093
Diana Dudziak
Falk Nimmerjahn
Heike Albert
Jeffrey V Ravetch
Mattias Collin
P2860
P304
15005-15009
P356
10.1073/PNAS.0808248105
P407
P577
2008-09-24T00:00:00Z