Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet
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Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and FunctionThe Macrophage Switch in Obesity DevelopmentLinking obesity with type 2 diabetes: the role of T-betAn MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation.RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages.Role of T cells in malnutrition and obesity.Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like peptide-1 secretion and reduces adipose tissue inflammationImmune regulation of metabolic homeostasis in health and disease.Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5.Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in ObesityPlaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice.Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistanceArterial Stiffening in Western Diet-Fed Mice Is Associated with Increased Vascular Elastin, Transforming Growth Factor-β, and Plasma Neuraminidase.Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance.Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.Obesity accelerates T cell senescence in murine visceral adipose tissue.The immune cell transcription factor T-bet: A novel metabolic regulator.Improved methodologies for the study of adipose biology: insights gained and opportunities ahead.Can metabolically healthy obesity be explained by diet, genetics, and inflammation?Adipose tissue inflammation in the pathogenesis of type 2 diabetes.Attenuated adipose tissue and skeletal muscle inflammation in obese mice with combined CD4+ and CD8+ T cell deficiency.Nutritional effects on T-cell immunometabolism.Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satietyInterleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation.Low alpha-synuclein levels in the blood are associated with insulin resistance.Modulation of Cell-Mediated Immunity to Suppress High Fat Diet-Induced Obesity and Insulin ResistanceThe impact of type 2 diabetes on the outcome of localized renal cell carcinoma.Adipocyte adaptive immunity mediates diet-induced adipose inflammation and insulin resistance by decreasing adipose Treg cells.Aging, Obesity, and Inflammatory Age-Related Diseases.Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons.Interferon-gamma released from omental adipose tissue of insulin-resistant humans alters adipocyte phenotype and impairs response to insulin and adiponectin release.
P2860
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P2860
Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Improved insulin sensitivity d ...... ell transcription factor T-bet
@en
type
label
Improved insulin sensitivity d ...... ell transcription factor T-bet
@en
prefLabel
Improved insulin sensitivity d ...... ell transcription factor T-bet
@en
P2093
P2860
P1433
P1476
Improved insulin sensitivity d ...... ell transcription factor T-bet
@en
P2093
Chi Teng Vong
Edward T Wargent
Emilie Stolarczyk
Esperanza Perucha
Graham M Lord
Ian Jackson
James B Canavan
Jane K Howard
Michael A Cawthorne
Nick Powell
P2860
P304
P356
10.1016/J.CMET.2013.02.019
P577
2013-04-01T00:00:00Z