Four-stranded DNA: cancer, gene regulation and drug development.
about
A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad DynamicsTargeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)A comparison of four different conformations adopted by human telomeric G-Quadruplex using Computer Simulations.Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Prospect of bioflavonoid fisetin as a quadruplex DNA ligand: a biophysical approach.Novel multistranded, alternative, plasmid and helical transitional DNA and RNA microarrays: implications for therapeutics.Separation of Quadruplex Polymorphism in DNA Sequences by Reversed-Phase Chromatography.Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genesStability and kinetics of G-quadruplex structuresDNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseasesEvaluation of binding selectivities and affinities of platinum-based quadruplex interactive complexes by electrospray ionization mass spectrometry.Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability.Polymorphism and resolution of oncogene promoter quadruplex-forming sequences.Epigenetic modification, dehydration, and molecular crowding effects on the thermodynamics of i-motif structure formation from C-rich DNA.Unfolding and conformational variations of thrombin-binding DNA aptamers: synthesis, circular dichroism and molecular dynamics simulations.Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysis.Resolution of quadruplex polymorphism by size-exclusion chromatography.A toolbox for predicting g-quadruplex formation and stabilityRelevance of G-quadruplex structures to pharmacogenetics.Folding thermodynamics of the hybrid-1 type intramolecular human telomeric G-quadruplex.Assessment of human telomeric G-quadruplex structures using surface-enhanced Raman spectroscopy.
P2860
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P2860
Four-stranded DNA: cancer, gene regulation and drug development.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Four-stranded DNA: cancer, gene regulation and drug development.
@en
type
label
Four-stranded DNA: cancer, gene regulation and drug development.
@en
prefLabel
Four-stranded DNA: cancer, gene regulation and drug development.
@en
P2860
P356
P1476
Four-stranded DNA: cancer, gene regulation and drug development.
@en
P2860
P304
P356
10.1098/RSTA.2007.0011
P407
P577
2007-12-01T00:00:00Z