Mitogen-activated protein kinases in heart development and diseases
about
Regulation of cardiac gene expression by KLF15, a repressor of myocardin activityMMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition.Cardiovascular effects in rats following exposure to a receptor tyrosine kinase inhibitorPak1 as a novel therapeutic target for antihypertrophic treatment in the heartActivation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemiaInhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol effluxComputational models reduce complexity and accelerate insight into cardiac signaling networksPARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms.Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPaseTranscriptome profiling of peripheral blood cells identifies potential biomarkers for doxorubicin cardiotoxicity in a rat modelSignaling responses after exposure to 5 alpha-dihydrotestosterone or 17 beta-estradiol in norepinephrine-induced hypertrophy of neonatal rat ventricular myocytesG alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).Prominent differences in left ventricular performance and myocardial properties between right ventricular and left ventricular-based pacing modes in ratsThe contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits.The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure.PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytesErbB signaling in cardiac development and disease.Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts.Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signalingMAPKs represent novel therapeutic targets for gastrointestinal motility disorders.Gαq protein carboxyl terminus imitation polypeptide GCIP-27 improves cardiac function in chronic heart failure rats.Inhibition of c-Jun N-terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient miceA novel cardioprotective p38-MAPK/mTOR pathway.Saffron extracts alleviate cardiomyocytes injury induced by doxorubicin and ischemia-reperfusion in vitro.Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts.Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.Human Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy.Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.Effects of Wenyangzhenshuai Granule on ERK1/2 and ERK5 activity in the myocardial tissue in a rabbit model of adriamycin-induced chronic heart failure.Identification of cardioprotective agents from traditional Chinese medicine against oxidative damage.Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium DesensitizationAbnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation.Asiatic acid inhibits cardiac hypertrophy by blocking interleukin-1β-activated nuclear factor-κB signaling in vitro and in vivo.Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females.Genetic inhibition of JNK3 ameliorates spinal muscular atrophy.MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension.Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndromeCaveolin and β1-integrin coordinate angiotensinogen expression in cardiac myocytesTowards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver.
P2860
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P2860
Mitogen-activated protein kinases in heart development and diseases
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mitogen-activated protein kinases in heart development and diseases
@en
type
label
Mitogen-activated protein kinases in heart development and diseases
@en
prefLabel
Mitogen-activated protein kinases in heart development and diseases
@en
P2860
P1433
P1476
Mitogen-activated protein kinases in heart development and diseases
@en
P2860
P304
P356
10.1161/CIRCULATIONAHA.106.679589
P407
P50
P577
2007-09-01T00:00:00Z