Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I
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Evidence that dynamin-2 functions as a signal-transducing GTPaseSNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patientsDirect dynamin-actin interactions regulate the actin cytoskeleton.Charcot-Marie-Tooth disease and intracellular trafficA feedback loop between dynamin and actin recruitment during clathrin-mediated endocytosisTriphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanismBuilding a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis.Dimeric endophilin A2 stimulates assembly and GTPase activity of dynamin 2Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s.The proline/arginine-rich domain is a major determinant of dynamin self-activationCrystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy.Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation.Lipid droplet breakdown requires dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes.An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.Flat clathrin lattices: stable features of the plasma membrane.The advantage of channeling nucleotides for very processive functionsDynamin GTPase domain mutants block endocytic vesicle formation at morphologically distinct stages.Dynamin 2 mutants linked to centronuclear myopathies form abnormally stable polymers.Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells.Garrotes, springs, ratchets, and whips: putting dynamin models to the test.The production of 'cell cortices' for light and electron microscopy.Probable mechanisms underlying interallelic complementation and temperature-sensitivity of mutations at the shibire locus of Drosophila melanogaster.Mechanics of dynamin-mediated membrane fission.Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cellsA new role for the dynamin GTPase in the regulation of fusion pore expansionYeast dynamin implicated in endocytic scission and the disassembly of endocytic components.Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1.Imaging single endocytic events reveals diversity in clathrin, dynamin and vesicle dynamics.Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms.Dynamin:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis.Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells.Dynamic instability of microtubules requires dynamin 2 and is impaired in a Charcot-Marie-Tooth mutantReprogramming the Dynamin 2 mRNA by Spliceosome-mediated RNA Trans-splicing.Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis.Dissecting dynamin's role in clathrin-mediated endocytosis.Dynamin 2 and human diseases.Role of dynamin 2 in the disassembly of focal adhesions.Dynamin-2 in nervous system disorders.
P2860
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P2860
Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Ubiquitously expressed dynamin ...... sembly than neuronal dynamin-I
@en
type
label
Ubiquitously expressed dynamin ...... sembly than neuronal dynamin-I
@en
prefLabel
Ubiquitously expressed dynamin ...... sembly than neuronal dynamin-I
@en
P2093
P2860
P356
P1476
Ubiquitously expressed dynamin ...... sembly than neuronal dynamin-I
@en
P2093
P2860
P304
P356
10.1091/MBC.8.12.2553
P577
1997-12-01T00:00:00Z