Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy
about
Cancer prevention with promising natural products: mechanisms of action and molecular targetsIn vivo and in vitro suppression of hepatocellular carcinoma by EF24, a curcumin analogDiphenyl difluoroketone: a potent chemotherapy candidate for human hepatocellular carcinomaAutophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog.Synthesis and evaluation of bisbenzylidenedioxotetrahydrothiopranones as activators of endoplasmic reticulum (ER) stress signaling pathways and apoptotic cell death in acute promyelocytic leukemic cells.Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs).Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993).Modulation of Wnt/β-catenin signaling pathway by bioactive food components.New perspectives of curcumin in cancer prevention.Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenograftsEF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties.EF24 and RAD001 potentiates the anticancer effect of platinum-based agents in human malignant pleural mesothelioma (MSTO-211H) cells and protects nonmalignant mesothelial (MET-5A) cells.p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.A synthetic compound, 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells.The Curcumin Analogue 1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one Induces Apoptosis and Downregulates E6 and E7 Oncogene Expression in HPV16 and HPV18-Infected Cervical Cancer Cells.Cyclodextrin-mediated entrapment of curcuminoid 4-[3,5-bis(2-chlorobenzylidene-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid] or CLEFMA in liposomes for treatment of xenograft lung tumor in rats.EF24 Suppresses Invasion and Migration of Hepatocellular Carcinoma Cells In Vitro via Inhibiting the Phosphorylation of Src.
P2860
Q27006530-C46FBADB-EB4E-4FC4-A0B7-1241FAA62370Q28484672-6DBD5429-EABE-40B9-9582-503FF3E1DA24Q34013776-F373CFE7-B6B2-4356-ABD1-C1BAF38B79CBQ34277096-911658BF-0A1D-456F-BC6F-61833664E182Q34435624-CF7880AE-8A83-4580-9F8E-0BA2D8852F23Q35034180-5B4A51F2-3871-4908-8CD5-995DCCDA6D01Q35225869-4EA61B67-EF67-4626-A4ED-D2F86595A6F7Q35360274-348FCB68-177C-40DC-8C06-9E8BB4F7F702Q36061114-374ACBBC-1C57-477D-81E4-C1BBCCDE28A4Q36957733-A485B714-3C8F-4B52-B419-FD0A6AEDE458Q37073686-97A2A9AD-9E3B-4F19-B706-6715CEADF3B9Q37109676-5F0C2EB4-EED6-4304-A294-64498281B029Q37590102-DC7E7C69-CBD7-4A89-90FD-583C235A475AQ38974983-970C2A1F-F17D-4954-B8F1-17F2262EBB08Q39340208-95ADAFB4-E1C1-49E0-ABA3-54ECA4F5C50FQ39424310-4119E693-5576-4461-86FA-ADA0AF685F3FQ40777873-EFCF9065-3033-4F99-B7C4-DA48B27DDF55Q42049243-7E4C4A45-0B4F-4310-A59E-5087D0B2A424Q42093589-4AFEF926-A90C-42BF-8CD6-77A6D0B11A85
P2860
Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Activation of the p38 pathway ...... potential combination strategy
@en
type
label
Activation of the p38 pathway ...... potential combination strategy
@en
prefLabel
Activation of the p38 pathway ...... potential combination strategy
@en
P2093
P2860
P1476
Activation of the p38 pathway ...... potential combination strategy
@en
P2093
Dennis Liotta
Fadlo R Khuri
James P Snyder
Jamie Purcell
Shala L Thomas
P2860
P304
P356
10.1016/J.BCP.2010.06.048
P407
P577
2010-07-06T00:00:00Z