Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy.
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Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes.Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene.FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuriaGenipin inhibits mitochondrial uncoupling protein 2 expression and ameliorates podocyte injury in diabetic mice.Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat modelDecreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsiaA plasminogen activator inhibitor type 1 mutant retards diabetic nephropathy in db/db mice by protecting podocytesCXCL16 and oxLDL are induced in the onset of diabetic nephropathy.Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2.Diabetic albuminuria is due to a small fraction of nephrons distinguished by albumin-stained tubules and glomerular adhesions.Oxidative stress, diabetes, and diabetic complications.Keap1 inhibition attenuates glomerulosclerosis.Augmenting podocyte injury promotes advanced diabetic kidney disease in Akita mice.Oxidative stress in early diabetic nephropathy: fueling the fire.Nox4 and diabetic nephropathy: with a friend like this, who needs enemies?Associations between structural and functional changes to the kidney in diabetic humans and mice.Metallothionein polymorphisms in pathological processes.High glucose increases metallothionein expression in renal proximal tubular epithelial cells.Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology.Metallothioneins and renal ageing.Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway.Impaired Albumin Uptake and Processing Promote Albuminuria in OVE26 Diabetic Mice.TEM stereometric analyses of glomeruli in aging OVE26 transgenic diabetic miceChronic Administration of Oil Palm (Elaeis guineensis) Leaves Extract Attenuates Hyperglycaemic-Induced Oxidative Stress and Improves Renal Histopathology and Function in Experimental Diabetes.Renoprotection From Diabetic Complications in OVE Transgenic Mice by Endothelial Cell Specific Overexpression of Metallothionein: A TEM Stereological Analysis.Podocyte-specific overexpression of metallothionein mitigates diabetic complications in the glomerular filtration barrier and glomerular histoarchitecture: a transmission electron microscopy stereometric analysis.Metallothionein over-expression in podocytes reduces adriamycin nephrotoxicity.Metallothionein deficiency exacerbates diabetic nephropathy in streptozotocin-induced diabetic mice.Lipid peroxidation regulates podocyte migration and cytoskeletal structure through redox sensitive RhoA signaling.
P2860
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P2860
Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Podocyte-specific overexpressi ...... reduces diabetic nephropathy.
@en
type
label
Podocyte-specific overexpressi ...... reduces diabetic nephropathy.
@en
prefLabel
Podocyte-specific overexpressi ...... reduces diabetic nephropathy.
@en
P2093
P2860
P356
P1476
Podocyte-specific overexpressi ...... n reduces diabetic nephropathy
@en
P2093
Edward C Carlson
Patricia M Kralik
Shirong Zheng
P2860
P304
P356
10.1681/ASN.2007080967
P577
2008-07-16T00:00:00Z