Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q.
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Abl family kinases regulate endothelial barrier function in vitro and in miceRho, ROCK and actomyosin contractility in metastasis as drug targetsStructure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11ROCKs as immunomodulators of strokeHydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injuryDirect Thrombin Inhibitors Prevent Left Atrial Remodeling Associated With Heart Failure in RatsAdherens junctions connect stress fibres between adjacent endothelial cellsA role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium.Adherens junctions remain dynamic.The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin.Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrityCCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.Calcium/Calmodulin-dependent protein kinase II delta 6 (CaMKIIdelta6) and RhoA involvement in thrombin-induced endothelial barrier dysfunction.Control of CXCR2 activity through its ubiquitination on K327 residue.Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunctionPrestroke proteomic changes in cerebral microvessels in stroke-prone, transgenic[hCETP]-Hyperlipidemic, Dahl salt-sensitive hypertensive ratsElevated cytokines, thrombin and PAI-1 in severe HCPS patients due to Sin Nombre virus.Heterotrimeric G proteins, focal adhesion kinase, and endothelial barrier function.Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway.Anaphylactic shock depends on endothelial Gq/G11.G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis.Breaking the VE-cadherin bonds.Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways.Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial CellsThe role of RhoA/Rho kinase pathway in endothelial dysfunctionRho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinson's Disease.Hyaluroan-regulated lymphatic permeability through S1P receptors is crucial for cancer metastasis.Regulation of pulmonary endothelial barrier function by kinases.Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injuryRho GEFs in endothelial junctions: Effector selectivity and signaling integration determine junctional response.CCL2 at the crossroad of cancer metastasis.Serotonin 5-HT7 receptor is critically involved in acute and chronic inflammation of the gastrointestinal tract.Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery.Cellular repressor of E1A stimulated genes enhances endothelial monolayer integrity.Branched actin networks push against each other at adherens junctions to maintain cell-cell adhesion.Statin pleiotropy prevents rho kinase-mediated intestinal epithelial barrier compromise induced by Blastocystis cysteine proteases.Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.
P2860
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P2860
Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Protein kinase C-related kinas ...... om Galpha12/13 and Galpha11/q.
@en
type
label
Protein kinase C-related kinas ...... om Galpha12/13 and Galpha11/q.
@en
prefLabel
Protein kinase C-related kinas ...... om Galpha12/13 and Galpha11/q.
@en
P2093
P2860
P356
P1476
Protein kinase C-related kinas ...... om Galpha12/13 and Galpha11/q.
@en
P2093
J Silvio Gutkind
Julie Gavard
P2860
P304
29888-29896
P356
10.1074/JBC.M803880200
P407
P577
2008-08-19T00:00:00Z