Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. - Wikidata - wikimedia - TriplyDB

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.

http://www.wikidata.org/entity/Q36950799

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A new WNT on the bone: WNT16, cortical bone thickness, porosity and fractures METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway.Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data.Impact of the environment on the skeleton: is it modulated by genetic factors?Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.Genome-wide Association Studies for Osteoporosis: A 2013 Update.Sex steroid actions in male bone Association between calcitonin receptor AluI gene polymorphism and bone mineral density: A meta-analysis.Role of WNT16 in the regulation of periosteal bone formation in female mice.Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone.The regulation of osteoclast differentiation by Wnt signals Osteoporosis: the emperor has no clothes Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.Bone Mass and Strength are Significantly Improved in Mice Overexpressing Human WNT16 in Osteocytes.The bone-sparing effects of estrogen and WNT16 are independent of each other The association of liver fat content and serum alanine aminotransferase with bone mineral density in middle-aged and elderly Chinese men and postmenopausal women.Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells.Unveiling the mysteries of the genetics of osteoporosis.The WNT system: background and its role in bone.The effects of body mass index on the hereditary influences that determine peak bone mass in mother-daughter pairs (KNHANES V).Non-synonymous WNT16 polymorphisms alleles are associated with different osteoarthritis phenotypes.Wnt16 is involved in intramembranous ossification and suppresses osteoblast differentiation through the Wnt/β-catenin pathway.Association Between Single Gene Polymorphisms and Bone Biomarkers and Response to Calcium and Vitamin D Supplementation in Young Adults Undergoing Military Training.Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network Analysis of SNP-SNP interactions and bone quantitative ultrasound parameter in early adulthood.Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.The RSPO3 gene as genetic markers for bone mass assessed by quantitative ultrasound in a population of young adults.Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure.Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice.Polymorphisms of the WNT16 gene are associated with the heel ultrasound parameter in young adults.Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo.Meta-Analysis of Genome-Wide Association Studies Identifies Novel Functional CpG-SNPs Associated with Bone Mineral Density at Lumbar Spine

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Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.

http://www.wikidata.org/entity/Q36950799

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2013 nî lūn-bûn

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2013年论文

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Meta-analysis of genome-wide s ...... ensity in premenopausal women.

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Meta-analysis of genome-wide s ...... ensity in premenopausal women.

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Meta-analysis of genome-wide s ...... ensity in premenopausal women.

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Journal of Bone and Mineral Research

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Meta-analysis of genome-wide s ...... ensity in premenopausal women.

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Audrey C Choh

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Bradford Towne

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Candace Kammerer

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Ching-Ti Liu

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Daniel L Koller

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David Goltzman

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Dongbing Lai

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Fiona McGuigan

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Francois Rousseau

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George McMahon

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P2860

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women

New sequence variants associated with bone mineral density

METAL: fast and efficient meta-analysis of genomewide association scans

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

Modelling of age-related bone loss using cross-sectional data.

Peak bone mass from longitudinal data: implications for the prevalence, pathophysiology, and diagnosis of osteoporosis

Genetic and environmental influences on bone mineral density in pre- and post-menopausal women.

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

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547-558

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10.1002/JBMR.1796

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3

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28

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Beate St Pourcain

Nicholas J. Timpson

Braxton D. Mitchell

Debbie A Lawlor

Howard J Edenberg

Christopher S. Kovacs

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2013-03-01T00:00:00Z

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232278483

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23074152

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3691010

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