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Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunitiesSpecific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tractThe Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.Morphine decreases enteric neuron excitability via inhibition of sodium channels.Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent mannerMorphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2Differential tolerance to morphine antinociception in assays of pain-stimulated vs. pain-depressed behavior in rats.Opioid receptors and associated regulator of G protein signaling are involved in the cathartic colon of rats.Emerging treatments in neurogastroenterology: a multidisciplinary working group consensus statement on opioid-induced constipationSensitization of enteric neurons to morphine by HIV-1 Tat protein.Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.Localization and regulation of fluorescently labeled delta opioid receptor, expressed in enteric neurons of mice.The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract.Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists.Divergent Effect of Dezocine, Morphine and Sufentanil on Intestinal Motor Function in Rats.Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents.Effects of methylnaltrexone on guinea pig gastrointestinal motility.Enhanced Sensitivity of α3β4 Nicotinic Receptors in Enteric Neurons after Long-Term Morphine: Implication for Opioid-Induced Constipation.6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand.Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives.The effect of gut microbiome on tolerance to morphine mediated antinociception in mice.Molecular physiology of enteric opioid receptors.Site and mechanism of morphine tolerance in the gastrointestinal tract.Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers.Opioidergic effects on enteric and sensory nerves in the lower GI tract: basic mechanisms and clinical implications.A randomised, placebo-controlled trial comparing the effects of tapentadol and oxycodone on gastrointestinal and colonic transit in healthy humans.Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone.Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance.New Formulation of Sustained Release Naloxone Can Reverse Opioid Induced Constipation Without Compromising the Desired Opioid Effects.Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse liability in rodents.Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation.CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward.Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350.Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model.Circular muscle contraction in the mice rectum plays a key role in morphine-induced constipation
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Morphine tolerance in the mouse ileum and colon
@en
type
label
Morphine tolerance in the mouse ileum and colon
@en
prefLabel
Morphine tolerance in the mouse ileum and colon
@en
P2093
P2860
P356
P1476
Morphine tolerance in the mouse ileum and colon
@en
P2093
Bichoy H Gabra
Gracious R Ross
William L Dewey
P2860
P304
P356
10.1124/JPET.108.143438
P407
P577
2008-08-05T00:00:00Z