Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters.
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Opposing Gatekeepers of Apical Sterol Transport: Niemann-Pick C1-Like 1 (NPC1L1) and ATP-Binding Cassette Transporters G5 and G8 (ABCG5/ABCG8)NPC1L1 and cholesterol transportTargets for current pharmacologic therapy in cholesterol gallstone disease.Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1.Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liverMechanism of resistance to dietary cholesterolThe chylomicron: relationship to atherosclerosis.Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver diseaseProtein mediators of sterol transport across intestinal brush border membrane.Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytesCreosote Bush (Larrea tridentata) Improves Insulin Sensitivity and Reduces Plasma and Hepatic Lipids in Hamsters Fed a High Fat and Cholesterol DietChanges in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men.New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation.Phytosterols protect against diet-induced hypertriglyceridemia in Syrian golden hamsters.Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.New insights into the molecular mechanism of intestinal fatty acid absorption.Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol.Statins as potential treatment for cholesterol gallstones: an attempt to understand the underlying mechanism of actions.Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression.Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1.Ezetimbe as potential treatment for cholesterol gallstones: the need for clinical trials.Curcuma oil ameliorates hyperlipidaemia and associated deleterious effects in golden Syrian hamsters.Chronic restraint stress induces intestinal inflammation and alters the expression of hexose and lipid transporters.Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance.Dietary calcium decreases plasma cholesterol by down-regulation of intestinal Niemann-Pick C1 like 1 and microsomal triacylglycerol transport protein and up-regulation of CYP7A1 and ABCG 5/8 in hamsters.
P2860
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P2860
Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Inhibiting intestinal NPC1L1 a ...... rol in Golden Syrian hamsters.
@en
type
label
Inhibiting intestinal NPC1L1 a ...... rol in Golden Syrian hamsters.
@en
prefLabel
Inhibiting intestinal NPC1L1 a ...... rol in Golden Syrian hamsters.
@en
P2093
P2860
P356
P1476
Inhibiting intestinal NPC1L1 a ...... erol in Golden Syrian hamsters
@en
P2093
John M Dietschy
Joyce J Repa
Stephen D Turley
P2860
P304
P356
10.1152/AJPGI.90372.2008
P577
2008-08-21T00:00:00Z