Generation of recombinant human parainfluenza virus type 1 vaccine candidates by importation of temperature-sensitive and attenuating mutations from heterologous paramyxoviruses.
about
Temperature-sensitive mutations for live-attenuated Rift Valley fever vaccines: implications from other RNA virusesHuman parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.Live bivalent vaccine for parainfluenza and influenza virus infections.Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Progress in the development of human parainfluenza virus vaccinesThe C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase RAlix serves as an adaptor that allows human parainfluenza virus type 1 to interact with the host cell ESCRT systemIdentification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primatesNonsegmented negative-strand viruses as vaccine vectors.Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes.Attenuated Human Parainfluenza Virus Type 1 (HPIV1) Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus (RSV) as a Bivalent HPIV1/RSV Vaccine.Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3' genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates.New generation live vaccines against human respiratory syncytial virus designed by reverse genetics.Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium.Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates.The C proteins of human parainfluenza virus type 1 (HPIV1) control the transcription of a broad array of cellular genes that would otherwise respond to HPIV1 infectionA novel human parainfluenza virus type 1 (HPIV1) with separated P and C genes is useful for generating C gene mutants for evaluation as live-attenuated virus vaccine candidates.Rational attenuation of a morbillivirus by modulating the activity of the RNA-dependent RNA polymerase.Attenuated Human Parainfluenza Virus Type 1 Expressing Ebola Virus Glycoprotein GP Administered Intranasally Is Immunogenic in African Green Monkeys.Progress in respiratory virus vaccine development
P2860
Q26796199-C9B9D650-61F4-4465-8321-B29049B9681BQ33653692-F400A83D-D156-4F1C-829E-0511A0F85286Q33788756-0D13C999-A6B1-4AE5-A9B0-4A29A26CA0A9Q34101229-F81BC2CF-E072-4B72-8183-BFF0D7CC8460Q34209872-CFB4FD83-D722-481C-95EB-54BC14D0CBC4Q34529862-DA617F27-CCB4-4BDC-955B-352C10972553Q34635209-E58DE81B-678C-4F8F-BFCA-6E765E44A2C5Q35076577-1D605BE0-7BEC-43AD-A8A1-83188E327DBDQ35139219-B777A7C7-B375-4F6B-BFBA-AA672874BA4BQ35924915-B4C933D2-8162-414E-8176-AE4D6B646728Q36086315-4A10F5B4-85FB-48EF-9654-DA226AC28B5FQ36088161-1D6692AF-54C5-465D-9D1D-4F9B00F9A57FQ36237057-FB55E5B3-845F-423A-ADB6-E3651EB55806Q36845674-BB907A7A-2382-4F7C-865D-A3E21C7714B7Q36898701-6F05A6AA-C230-48B1-96AF-A61B34E85617Q37099848-EBD4B4B5-53B3-40D0-A8F2-878D6E1E56FCQ37468212-21DDC1BD-EE34-47E7-B2CF-0BAD45954373Q39612879-1E14A341-A127-4281-8387-3BB431482070Q40067156-DBCDA5DB-BCBB-4E63-AAFD-CA98B41E583AQ56894869-7BDFA78D-D0F2-4101-B1E0-91E4E57D47EA
P2860
Generation of recombinant human parainfluenza virus type 1 vaccine candidates by importation of temperature-sensitive and attenuating mutations from heterologous paramyxoviruses.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Generation of recombinant huma ...... heterologous paramyxoviruses.
@en
type
label
Generation of recombinant huma ...... heterologous paramyxoviruses.
@en
prefLabel
Generation of recombinant huma ...... heterologous paramyxoviruses.
@en
P2093
P2860
P1433
P1476
Generation of recombinant huma ...... heterologous paramyxoviruses.
@en
P2093
Brian R Murphy
Jason T Newman
Jeffrey M Riggs
Josephine M McAuliffe
Mario H Skiadopoulos
Peter L Collins
Sonja R Surman
Teresa A Mulaikal
P2860
P304
P356
10.1128/JVI.78.4.2017-2028.2004
P407
P577
2004-02-01T00:00:00Z