Brain SIRT1: anatomical distribution and regulation by energy availability. - Wikidata - wikimedia - TriplyDB

Brain SIRT1: anatomical distribution and regulation by energy availability.

Brain SIRT1: anatomical distribution and regulation by energy availability.

http://www.wikidata.org/entity/Q36962837

about

SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.Protective effects and mechanisms of sirtuins in the nervous system Sirtuin 1 and sirtuin 3: physiological modulators of metabolism SIRT1 and SIRT2: emerging targets in neurodegeneration SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals The promise and perils of HDAC inhibitors in neurodegeneration SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels Sirtuin activity in dentate gyrus contributes to chronic stress-induced behavior and extracellular signal-regulated protein kinases 1 and 2 cascade changes in the hippocampus.Regulation of histone acetylation in the hippocampus of chronically stressed rats: a potential role of sirtuins.SIRT1 is essential for normal cognitive function and synaptic plasticity Hypothalamic Sirt1 regulates food intake in a rodent model system.Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.Effect of feeding regimens on circadian rhythms: implications for aging and longevity.A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability.Pharmacological manipulations of CNS sirtuins: potential effects on metabolic homeostasis.Minireview: Central Sirt1 regulates energy balance via the melanocortin system and alternate pathways.Induction of leptin resistance by activation of cAMP-Epac signaling.Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals Programmed hyperphagia secondary to increased hypothalamic SIRT1 The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.SIRT1 regulation of wakefulness and senescence-like phenotype in wake neurons Differential expression of sirtuin family members in the developing, adult, and aged rat brain.Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems.Does hypothalamic SIRT1 regulate aging?Sirtuin-1 regulation of mammalian metabolism Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats.An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.SIRT1 in the brain-connections with aging-associated disorders and lifespan SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance.Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons.Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats Differential effects of exercise and dietary docosahexaenoic acid on molecular systems associated with control of allostasis in the hypothalamus and hippocampus.Differential expression of sirtuins in the aging rat brain SIRT1 and CLOCK 3111T> C combined genotype is associated with evening preference and weight loss resistance in a behavioral therapy treatment for obesity.SIRT1 Relays Nutritional Inputs to the Circadian Clock Through the Sf1 Neurons of the Ventromedial Hypothalamus.

P2860

Q24630974-79C389D7-061D-41F0-9315-F289F203501F Q26825585-0AE3AD58-4A51-4F08-8CB1-768D5CCF19D5 Q26828607-31B6F3CB-E21C-4371-AD08-4A1F7B986A0B Q26864929-59CA3A3D-A2CE-4F6A-8588-687BC4912B3E Q27322925-E07CD0B1-6479-4AFD-80C0-FD1FD0ABA42D Q28087539-AFC2B545-94E8-4F5D-8B30-5147E7AB91CE Q28512048-CFC2EDCA-D28F-4C98-BDED-E07DDA26443C Q28572486-A32FCFF4-EE6D-4894-9BC0-8417A5FC0D1E Q28585910-DE6A1DC6-A431-4029-9A14-1737C63F2528 Q30411171-33248116-F426-48A0-9942-8EA12F95263E Q30428450-2A3DBBB6-6440-4F1B-9EC2-F07C67E01CD1 Q30496047-DE46D1C2-CEBA-43EC-9B1C-039A554DD317 Q33519539-1C130C50-D050-4753-B5DB-9ABB1FE32C02 Q33720343-F2F26A38-9354-464B-BC9A-9EC20FC3582A Q33722180-5CA56C75-87D1-4171-B8DC-008116A57DC9 Q33750102-6DD07B35-BC31-4177-960A-CBD98D8836D6 Q33857250-494E0E02-3939-491E-AEE6-F2029D79A48C Q34131683-2578C42B-30C5-4A14-A275-0F3AF5EBB6C9 Q34167234-1D1F0130-D83C-419A-B88A-B31583983016 Q34247997-815C61A7-75D1-4947-A8D1-2903239474EA Q34286417-045F7E2C-C4B5-4E7F-98AE-B85004AF5376 Q34372365-64FDE75C-3D3A-4FDB-81B4-840BA6E645CC Q34623319-B178A103-99E2-4130-95E6-79F1B4A250AD Q34685422-D0CD3D07-0708-45D9-9B42-4C013EBCA175 Q34718745-A5413B80-CB5F-43A7-AC82-67939ABFB254 Q34726061-E6253A07-CCCF-474C-A40F-50EE2360F6EA Q34730013-65CD3B89-3B6C-42D0-8472-0F4201ED2B41 Q34763314-D41A6AC7-5B5C-4BD5-9885-4D443BF00D78 Q34966735-7DC39AD9-798E-4AC1-9592-3335A92C3FE9 Q35068878-C813F28C-760D-467D-A96C-347CB1DC4143 Q35088823-4AAAA7DB-6407-4E60-A009-7730CD0CE711 Q35135962-0B312901-90E2-4986-B22B-949CC0D650A5 Q35158382-09858E01-49F2-400E-834A-BB5B4CE55071 Q35211715-94180D79-B824-4B19-98DC-C98C52070666 Q35377645-E616B49D-78BA-4277-8FC8-E693F6893238 Q35405402-2A4DF620-70D6-431C-8976-59B57AE9BD2C Q35576172-818B7765-8AEE-440E-B60A-29194D568736 Q35584969-398C21F5-AA0C-4450-A09B-7CD7A828BA76 Q35598108-2CCB3201-5236-425E-AFB9-4F5C7ABF241E Q35603361-B99AFF40-7324-4E94-B81A-0D0D142AC435

P2860

Brain SIRT1: anatomical distribution and regulation by energy availability.

http://www.wikidata.org/entity/Q36962837

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Brain SIRT1: anatomical distribution and regulation by energy availability.

@en

type

label

Brain SIRT1: anatomical distribution and regulation by energy availability.

@en

prefLabel

Brain SIRT1: anatomical distribution and regulation by energy availability.

@en

P1433

Q36962837-EE0A72E1-4A3C-46C7-98C0-287CE05E2763

P1476

Q36962837-94860C00-40D4-4E7C-AFBD-5BEC6F72E0E5

P2093

Q36962837-21F0A742-4911-481F-8A67-E75E3AEFCE22

Q36962837-50A0F08C-5C09-4F89-9052-54CF606EF7F5

Q36962837-7E383595-D196-49F7-851F-548C11FEA5B3

Q36962837-87A74BA6-FFE8-4EF9-9B5A-6A7F3FFA2BB4

Q36962837-A31A1739-3FFE-44A4-BC08-61350FBBE299

Q36962837-B39C1B02-B8A0-406B-AC17-B9552BD9FA86

P2860

Q36962837-08C3D5DE-F48A-4383-9383-C68CA880D7C4

Q36962837-0B12BD18-6496-4AAF-8D68-CC85788C105C

Q36962837-12F37A0B-C983-476D-8381-F7E2ED9ABDCD

Q36962837-1C554A42-F199-42C5-84DA-AC5C3E1CDC72

Q36962837-21D4C811-1647-4B4B-A771-FB815748D043

Q36962837-22D24870-2651-4070-94BE-0AF453E9A8FD

Q36962837-2E7F161F-F9E4-416E-9432-A03400170A42

Q36962837-3E7FF524-7F99-4730-8F43-A9B362702EF7

Q36962837-42453FB0-F9FB-479D-8FED-8A384555B725

Q36962837-4499F7EB-4B61-4B8E-986D-716C17F7AF8A

P304

Q36962837-1B917D9D-3FC8-45D3-B38A-D756A25243AF

P31

Q36962837-149B49F7-226D-4822-81AE-193D18948C7C

P356

Q36962837-80EDD1BB-F7CD-4E53-ABD4-4256D018B18A

P407

Q36962837-FE3F36ED-A01E-4919-93C1-E3E393E13BDE

P433

Q36962837-EB8ADD85-1C5D-4033-AC9A-F5CAAA1D3A4F

P478

Q36962837-E4B88B3C-E340-4F3C-B070-058458A7A375

P50

Q36962837-18863095-C9FE-4270-A51D-64D7B7CB4679

Q36962837-411098F1-FA17-49C6-97E7-BB251E70C1DC

P577

Q36962837-8CA60E3F-1315-4320-A7D1-7F56523FC11B

P5875

Q36962837-7808C2C5-ECE4-4E19-A419-F812B0996178

P698

Q36962837-F1A122BB-2CBC-465D-945C-496344019A3D

P932

Q36962837-AEAED075-ECA8-4480-A982-1C48CCA2625C

P356

JNEUROSCI.3257-08.2008

P1433

Journal of Neuroscience

P1476

Brain SIRT1: anatomical distribution and regulation by energy availability.

@en

P2093

Angie L Bookout

http://www.w3.org/2001/XMLSchema#string

Charlotte E Lee

http://www.w3.org/2001/XMLSchema#string

Jason Anderson

http://www.w3.org/2001/XMLSchema#string

Joel K Elmquist

http://www.w3.org/2001/XMLSchema#string

Roberto Coppari

http://www.w3.org/2001/XMLSchema#string

Syann Lee

http://www.w3.org/2001/XMLSchema#string

P2860

Positional cloning of the mouse obese gene and its human homologue

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

DBC1 is a negative regulator of SIRT1

Negative regulation of the deacetylase SIRT1 by DBC1

SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

P304

9989-9996

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1523/JNEUROSCI.3257-08.2008

http://www.w3.org/2001/XMLSchema#string

P407

P433

40

http://www.w3.org/2001/XMLSchema#string

P478

28

http://www.w3.org/2001/XMLSchema#string

P50

Kevin W. Williams

Giorgio Ramadori

P577

2008-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23294618

http://www.w3.org/2001/XMLSchema#string

P698

18829956

http://www.w3.org/2001/XMLSchema#string

P932

2578850

http://www.w3.org/2001/XMLSchema#string