Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
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A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.Nicotinic receptor modulation to treat alcohol and drug dependenceHow can we use our knowledge of alcohol-tobacco interactions to reduce alcohol use?Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validityEffects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.Reward, addiction, withdrawal to nicotine.Decreasing nicotinic receptor activity and the spatial learning impairment caused by the NMDA glutamate antagonist dizocilpine in rats.Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence.Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system.Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers.Translational Research on Nicotine Dependence.Neurophysiology of Nicotine AddictionNicotinic Acetylcholine Receptor (nAChR) Dependent Chorda Tympani Taste Nerve Responses to Nicotine, Ethanol and Acetylcholine.Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380.Nicotinic acetylcholine receptors containing the α4 subunit modulate alcohol rewardPKCε phosphorylates α4β2 nicotinic ACh receptors and promotes recovery from desensitizationDevelopment of an oral operant nicotine/ethanol co-use model in alcohol-preferring (p) rats.Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female ratsChronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.A new radioligand binding assay to measure the concentration of drugs in rodent brain ex vivo.Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse.Recent Advances in Nicotinic Receptor Signaling in Alcohol Abuse and Alcoholism.Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats.Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal.Effects of caffeine on alcohol consumption and nicotine self-administration in ratsChemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in ratsEffects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependenceChronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brainAcute activation, desensitization and smoldering activation of human acetylcholine receptors.Rat animal models for screening medications to treat alcohol use disorders.Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats.Rodent ultrasonic vocalizations as biomarkers of future alcohol use: A predictive analytic approach.The effect of sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats.The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption.Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs).Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats.Nicotine-induced enhancement of Pavlovian alcohol-seeking behavior in rats.Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats.
P2860
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P2860
Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Effects of sazetidine-A, a sel ...... d alcohol-preferring (P) rats.
@en
type
label
Effects of sazetidine-A, a sel ...... d alcohol-preferring (P) rats.
@en
prefLabel
Effects of sazetidine-A, a sel ...... d alcohol-preferring (P) rats.
@en
P2093
P2860
P1433
P1476
Effects of sazetidine-A, a sel ...... d alcohol-preferring (P) rats.
@en
P2093
Amir H Rezvani
Brian E McDowell
Cori Wells
Edward D Levin
Jed E Rose
Kenneth J Kellar
Lawrence Lumeng
Mikell A Paige
Milton L Brown
P2860
P2888
P304
P356
10.1007/S00213-010-1878-8
P577
2010-06-10T00:00:00Z