about
Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymesThe pharmacokinetic and pharmacodynamic consequences of the co-administration of lamotrigine and a combined oral contraceptive in healthy female subjectsCytochrome P4502C9: an enzyme of major importance in human drug metabolismRegulation of uridine diphosphate glucuronosyltransferase during the acute-phase responseQuantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationInterindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.MODEL-BASED LAMOTRIGINE CLEARANCE CHANGES DURING PREGNANCY: CLINICAL IMPLICATION.Menthol's potential effects on nicotine dependence: a tobacco industry perspective.Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria.Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance.Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism.Human hepatic UGT2B15 developmental expression.Safety and Efficacy of Sorafenib in Patients with Hepatocellular Carcinoma (HCC) and Child-Pugh A versus B CirrhosisInduction and autoinduction properties of rifamycin derivatives: a review of animal and human studies.Pharmacogenomics of human UDP-glucuronosyltransferase enzymes.In vitro-in vivo correlations for drugs eliminated by glucuronidation: investigations with the model substrate zidovudine.Intracellular nucleotide pools and ratios as tools for monitoring dedifferentiation of primary porcine hepatocytes in cultureInhibition of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 Regulates the Hepatobiliary Excretion and Plasma Exposure of Thienorphine and Its Glucuronide Conjugate.Pharmacogenetics of analgesics: toward the individualization of prescription.Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.Quantitative determination of common urinary odorants and their glucuronide conjugates in human urine.N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases.Substrate selectivity of human intestinal UDP-glucuronosyltransferases (UGTs): in silico and in vitro insights.Hormonal regulation of hepatic drug biotransformation and transport systems.Gene replacement therapy for genetic hepatocellular jaundice.Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition.Regulation of uridine diphosphate-glucuronosyltransferase 1A3 activity by protein phosphorylation.Expression and inducibility of UDP-glucuronosyltransferase 1As in MCF-7 human breast carcinoma cells.Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.Oxcarbazepine: pharmacokinetic interactions and their clinical relevance.The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro.Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.Mechanism of stimulation of microsomal UDP-glucuronosyltransferase by UDP-N-acetylglucosamine.Carrier-mediated transport of intact UDP-glucuronic acid into the lumen of endoplasmic-reticulum-derived vesicles from rat liver.Carrier-mediated transport of uridine diphosphoglucuronic acid across the endoplasmic reticulum membrane is a prerequisite for UDP-glucuronosyltransferase activity in rat liverUridine diphosphoxylose enhances hepatic microsomal UDP-glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane.Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity.
P2860
Q24336118-E3092218-093F-4DE3-9604-3001F0EAF6F9Q24678717-12CC839D-E67D-43FC-9F52-181D5AFAB3DEQ24683497-864E08C0-D374-4C30-B81F-E5EFED6FEDDBQ28582517-49AF5211-3FB6-4C15-8815-8213332E09F5Q31034463-12F56EB3-CBCF-4D38-896B-2102D719B607Q33451969-DE5A5D5A-13B5-4677-AD8B-E9D05021BB38Q33683865-A49FB4BD-4301-4C12-8172-87BF4CADCAB0Q33877118-F1F7C75A-3C39-42EE-9494-B17D03DE3172Q33981168-46205871-6357-4091-8984-9E2CAB6088F3Q34057508-E449C373-7DD2-4B2B-A52A-4C8CE8180B9DQ34093111-EC898CF1-72E3-48F5-940B-AD6AB9D4F944Q34325249-E7D28899-1762-4687-83CE-7DA7BF5DECE5Q34479006-D61B9789-7125-47E8-B0E4-3834423156E7Q34737080-FAC2E7D5-5FE6-4194-9A2F-91471B95DCF8Q35030418-759B1104-040A-4AD4-B4E5-81D03A25B9C9Q35030873-CAA127AF-A39F-4A6C-A57C-87C512017CB6Q35157993-EDD154D4-C49D-4E42-AF74-3BC9AC4C4B94Q35804150-172E11DD-C6C8-48C1-9422-AA32D0FD36C3Q36255237-5E4BE89F-F340-4EBC-8EBB-BD274FC3AAE1Q37159255-3BE9E3A9-55EC-4D6F-8EE6-F56AF6893B2AQ37205954-F8EA36C2-F6BD-43D0-947D-6E403E609A79Q37230200-798E7E7B-CE99-41AE-81C3-42712F736731Q37471079-C51E1855-B274-43DC-99D0-AB351907815CQ37512783-B4CA7D70-9CE1-438B-929D-778DB2990773Q37857239-2BFBAB0E-CE16-40B4-B578-3627A75D2FF1Q38086603-227FAB75-7793-4658-948B-544826320F24Q38165145-F18B4C97-F406-4B2C-8259-5DDC0FAD48C2Q38260248-F8D18E69-C441-4433-9067-B83C263979A7Q38811693-9DD6B562-79B4-40CA-9F67-40C8425D8698Q38861758-4514F75C-8075-4B48-866F-97306FE6A252Q39477246-1F201F2B-943A-4D46-9945-E9840C637641Q39921876-27A9C06E-F5D7-4632-B42F-9C7DA6E5C24BQ40739805-2AFE2BC4-3DC5-40CB-AA9F-C4658531F53FQ41064018-D2AEE0A9-171B-4AA3-B2B2-8FE72DE0E972Q41222750-80B73314-DA5D-4739-A2B3-B8FEB5B1FE6AQ41953101-05DA71C2-C06E-41A8-A0FC-AC0E0EF23555Q42091520-07541725-0F16-4EC3-A4A9-4EED3EF17D55Q42120449-3AA85801-044B-4952-BA5A-1FCB79CAE34BQ42171040-1EC5240F-B545-4A90-8FCF-492724F4028AQ42264778-90E7F33C-1842-4EDA-8D95-D8C3E967B0DB
P2860
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Drug glucuronidation in humans.
@en
type
label
Drug glucuronidation in humans.
@en
prefLabel
Drug glucuronidation in humans.
@en
P1476
Drug glucuronidation in humans.
@en
P2093
Mackenzie PI
P304
P356
10.1016/0163-7258(91)90065-T
P577
1991-01-01T00:00:00Z