Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
about
Fibrillogenic propensity of the GroEL apical domain: a Janus-faced minichaperoneUse of thallium to identify monovalent cation binding sites in GroELVisualizing GroEL/ES in the Act of Encapsulating a Folding ProteinCrystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 A resolutionB-Cell Epitopes in GroEL of Francisella tularensisChaperonin GroEL uses asymmetric and symmetric reaction cycles in response to the concentration of non-native substrate proteinsDynamics, flexibility, and allostery in molecular chaperoninsIntrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR.Out-of-equilibrium conformational cycling of GroEL under saturating ATP concentrationsSelf-assembly of the chaperonin GroEL nanocage induced at submicellar detergentGroEL actively stimulates folding of the endogenous substrate protein PepQThe C-terminal tails of the bacterial chaperonin GroEL stimulate protein folding by directly altering the conformation of a substrate proteinEngineering a nanopore with co-chaperonin function.Setting the chaperonin timer: the effects of K+ and substrate protein on ATP hydrolysis.Measuring how much work the chaperone GroEL can do.Substrate protein switches GroE chaperonins from asymmetric to symmetric cycling by catalyzing nucleotide exchange.The group II chaperonin Mm-Cpn binds and refolds human γD crystallin.Measurement of 15N longitudinal relaxation rates in 15NH4+ spin systems to characterise rotational correlation times and chemical exchange.Asp-52 in combination with Asp-398 plays a critical role in ATP hydrolysis of chaperonin GroEL.Denatured proteins facilitate the formation of the football-shaped GroEL-(GroES)2 complex.Disassembly/reassembly strategy for the production of highly pure GroEL, a tetradecameric supramolecular machine, suitable for quantitative NMR, EPR and mutational studies.
P2860
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P2860
Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
@en
type
label
Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
@en
prefLabel
Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
@en
P2093
P2860
P356
P1476
Setting the chaperonin timer: a two-stroke, two-speed, protein machine.
@en
P2093
George H Lorimer
Jennifer S Gresham
John P Grason
P2860
P304
17339-17344
P356
10.1073/PNAS.0807418105
P407
P577
2008-11-06T00:00:00Z