Human simulated studies of aztreonam and aztreonam-avibactam to evaluate activity against challenging gram-negative organisms, including metallo-β-lactamase producers.
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Beyond Susceptible and Resistant, Part III: Treatment of Infections due to Gram-Negative Organisms Producing CarbapenemasesImpact of the New Delhi metallo-beta-lactamase on beta-lactam antibioticsAvibactam and Class C -Lactamases: Mechanism of Inhibition, Conservation of the Binding Pocket, and Implications for ResistanceAntibiotics in the clinical pipeline at the end of 2015.Interaction of Avibactam with Class B Metallo-β-Lactamases.In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates.Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-β-lactamase-producing Enterobacteriaceae in a murine thigh infection model.In vivo activities of simulated human doses of cefepime and cefepime-AAI101 against multidrug-resistant Gram-negative Enterobacteriaceae.β-Lactam Antibiotics Renaissance.Successful Treatment of Bloodstream Infection Due to Metallo-β-Lactamase-Producing Stenotrophomonas maltophilia in a Renal Transplant PatientCharacterizing in vivo pharmacodynamics of carbapenems against Acinetobacter baumannii in a murine thigh infection model to support breakpoint determinations.In vitro activities of ceftazidime-avibactam and aztreonam-avibactam against 372 Gram-negative bacilli collected in 2011 and 2012 from 11 teaching hospitals in China.In vivo efficacy of human simulated regimens of carbapenems and comparator agents against NDM-1-producing Enterobacteriaceae.New antibiotics for bad bugs: where are we?Current and future treatment options for infections caused by multidrug-resistant Gram-negative pathogens.Development of novel antibacterial drugs to combat multiple resistant organisms.Antibiotics Clinical Development and Pipeline.The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance.Pharmacokinetics and pharmacodynamics in antibiotic dose optimization.One ring to rule them all: Current trends in combating bacterial resistance to the β-lactamsPharmacodynamics of Cefepime Combined with Tazobactam against Clinically Relevant Enterobacteriaceae in a Neutropenic Mouse Thigh Model.A review of the pharmacokinetics and pharmacodynamics of aztreonam.The antibiotic pipeline for multi-drug resistant gram negative bacteria: what can we expect?Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam.In Vitro Discordance with In Vivo Activity: Humanized Exposures of Ceftazidime-Avibactam, Aztreonam, and Tigecycline Alone and in Combination against New Delhi Metallo-β-Lactamase-Producing Klebsiella pneumoniae in a Murine Lung Infection Model.Prediction of in vivo and in vitro infection model results using a semimechanistic model of avibactam and aztreonam combination against multidrug resistant organisms.In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms.In Vitro Activity of Cefepime/AAI101 and Comparators against Cefepime Non-susceptible EnterobacteriaceaeRapid Flow Cytometry Test for Identification of Different Carbapenemases in EnterobacteriaceaeApplication of "Precision Medicine" Through the Molecular Characterization of Extensively Drug-Resistant Klebsiella pneumoniae in a Multivisceral Transplant Patient.High Rates of Nonsusceptibility to Ceftazidime-avibactam and Identification of New Delhi Metallo-β-lactamase Production in Enterobacteriaceae Bloodstream Infections at a Major Cancer Center.Pharmacological aspects and spectrum of action of ceftazidime-avibactam: a systematic review.New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis.Avibactam Pharmacokinetic/Pharmacodynamic Targets.Treatment of Infections Caused by Extended-Spectrum-Beta-Lactamase-, AmpC-, and Carbapenemase-Producing Enterobacteriaceae.Empirical antimicrobial treatment in haemato-/oncological patients with neutropenic sepsis.
P2860
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P2860
Human simulated studies of aztreonam and aztreonam-avibactam to evaluate activity against challenging gram-negative organisms, including metallo-β-lactamase producers.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Human simulated studies of azt ...... metallo-β-lactamase producers.
@en
type
label
Human simulated studies of azt ...... metallo-β-lactamase producers.
@en
prefLabel
Human simulated studies of azt ...... metallo-β-lactamase producers.
@en
P2860
P356
P1476
Human simulated studies of azt ...... metallo-β-lactamase producers.
@en
P2093
David P Nicolau
Jared L Crandon
P2860
P304
P356
10.1128/AAC.01989-12
P407
P577
2013-05-06T00:00:00Z