HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions - Wikidata - wikimedia - TriplyDB

HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

http://www.wikidata.org/entity/Q36972650

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To build a synapse: signaling pathways in neuromuscular junction assembly Linking replication stress with heterochromatin formation Transcriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24 HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.HP1gamma function is required for male germ cell survival and spermatogenesis.Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.Heterochromatin protein 1 (HP1) proteins do not drive pericentromeric cohesin enrichment in human cells.Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10 UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiation Hdac3 is essential for the maintenance of chromatin structure and genome stability.Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1α and β in lamin A/C knock-down cells.Loss of Atrx sensitizes cells to DNA damaging agents through p53-mediated death pathways N-terminal phosphorylation of HP1{alpha} promotes its chromatin binding Large scale expression changes of genes related to neuronal signaling and developmental processes found in lateral septum of postpartum outbred mice.Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing.Nucleosome compaction facilitates HP1γ binding to methylated H3K9.Chromatin modifications and the DNA damage response to ionizing radiation.Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells.Chromatin remodeling finds its place in the DNA double-strand break response.The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic Heterochromatin protein 1 is recruited to various types of DNA damage.The emerging role of HP1 in the DNA damage response.Revisiting the role of heterochromatin protein 1 in DNA repair.HP1: heterochromatin binding proteins working the genome.Chromatin and the DNA damage response: the cancer connection.Biochemical and structural properties of heterochromatin protein 1: understanding its role in chromatin assembly.H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes.An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions.N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity.Heterochromatin protein 1 expression is reduced in human thyroid malignancy.Heterochromatin and the molecular mechanisms of 'parent-of-origin' effects in animals.CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing.Function of heterochromatin protein 1 during DNA repair.De Novo Truncating Mutations in the Kinetochore-Microtubules Attachment Gene CHAMP1 Cause Syndromic Intellectual Disability.A hypomorphic Cbx3 allele causes prenatal growth restriction and perinatal energy homeostasis defects.Up-regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex.

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HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

http://www.wikidata.org/entity/Q36972650

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2008 nî lūn-bûn

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2008年の論文

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HP1-beta is required for devel ...... ex and neuromuscular junctions

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HP1-beta is required for devel ...... ex and neuromuscular junctions

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HP1-beta is required for devel ...... ex and neuromuscular junctions

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HP1-beta is required for devel ...... ex and neuromuscular junctions

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Dimitris Kioussis

http://www.w3.org/2001/XMLSchema#string

Girdhar G Sharma

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Guozheng Wang

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Ingrid Reisert

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Jeremy P Brown

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Jörn Bullwinkel

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Mustafa Billur

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Raj K Pandita

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Rebecca Aucott

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Reinald Fundele

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P2860

Regulation of chromatin structure by site-specific histone H3 methyltransferases

A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation

Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner

Mammalian chromodomain proteins: their role in genome organisation and expression

Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins

Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells

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10.1083/JCB.200804041

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4

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183

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19015315

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2582898

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