PIK3CA(H1047R)- and Her2-initiated mammary tumors escape PI3K dependency by compensatory activation of MEK-ERK signaling.
about
ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor.Targeting the Breast Cancer Kinome.A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib.
P2860
PIK3CA(H1047R)- and Her2-initiated mammary tumors escape PI3K dependency by compensatory activation of MEK-ERK signaling.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
PIK3CA(H1047R)- and Her2-initi ...... tivation of MEK-ERK signaling.
@en
type
label
PIK3CA(H1047R)- and Her2-initi ...... tivation of MEK-ERK signaling.
@en
prefLabel
PIK3CA(H1047R)- and Her2-initi ...... tivation of MEK-ERK signaling.
@en
P2093
P2860
P356
P1433
P1476
PIK3CA(H1047R)- and Her2-initi ...... tivation of MEK-ERK signaling.
@en
P2093
A Isabella
C L Arteaga
P2860
P2888
P304
P356
10.1038/ONC.2015.377
P407
P577
2015-12-07T00:00:00Z